Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI)
المؤلفون المشاركون
Pratesi, Riccardo
Barra, Filipe Ramos
Sobrinho, Alaor Barra
Barra, Renato Ramos
Magalhães, Mayra Teixeira
Aguiar, Laira Rodrigues
Albuquerque, Gabriela Feitosa Lins de
Costa, Rodrigo Pepe
Farage, Luciano
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the performance of contrast-enhanced mammography (CEM) compared to magnetic resonance imaging (MRI) for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in women with newly diagnosed breast cancer.
Methods.
The institutional review board approved this study.
This prospective study included women with newly diagnosed breast cancer who underwent breast CEM and MRI at the end of the last cycle of NAC and before definitive surgery.
Size of residual malignancy on post-NAC CEM and MRI was compared with surgical pathology.
Agreements and correlations of CEM and MRI measurements with histological size were assessed.
Results.
Thirty-three patients were included with a mean age of 45 years (range 22–76).
The sensitivity, specificity, and positive and negative predictive value for detection of residual disease of CEM were 76%, 87.5%, 95%, and 86.4%, and those of MRI were 92%, 75%, 92%, and 75%.
Comparing CEM to MRI, the mean difference was −0.8 cm, concordance coefficient was 0.7, and Pearson correlation was 0.7 (p = 0.0003).
The concordance coefficient between measurements of each imaging modality and pathologic tumor size was 0.7 for CEM and 0.4 for MRI.
Pearson correlation was 0.8 for CEM and 0.5 for MRI.
Mean differences between CEM, MRI, and residual histopathological tumor size were 0.8 cm and 1.8 cm, respectively.
Conclusions.
CEM has good correlation and agreement with histopathology for measuring residual disease after NAC.
CEM was comparable to MRI, showing high positive predictive value and specificity for detecting residual disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Barra, Filipe Ramos& Sobrinho, Alaor Barra& Barra, Renato Ramos& Magalhães, Mayra Teixeira& Aguiar, Laira Rodrigues& Albuquerque, Gabriela Feitosa Lins de…[et al.]. 2018. Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI). BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129219
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Barra, Filipe Ramos…[et al.]. Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI). BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1129219
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Barra, Filipe Ramos& Sobrinho, Alaor Barra& Barra, Renato Ramos& Magalhães, Mayra Teixeira& Aguiar, Laira Rodrigues& Albuquerque, Gabriela Feitosa Lins de…[et al.]. Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI). BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129219
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129219
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر