Long-Term Prognosis of Suspected Myocarditis and Cardiomyopathy Associated with Viral Infection of the Myocardial Tissue: A Meta-Analysis of Cohort Studies
المؤلفون المشاركون
Chen, Wen-Hao
Guo, You-Sheng
Zhang, Dong-Hui
Zhang, Huan-Ji
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Aim.
Myocarditis and cardiomyopathy impose a substantial economic burden on society.
Many studies have examined the effects of various predictors on the prognosis of these diseases, such as the left ventricular systolic function, the New York Heart Association glomerular filtration rate, the QT interval, and the presence of viruses.
In the present study, we conducted a meta-analysis of cohort studies to investigate the significance of the presence of viruses in the myocardial tissue on the prognosis of these diseases.
Methods.
The Embase, PubMed, and Cochrane library databases were searched for relevant literature that had been published between January 1, 1964 and August 14, 2018.
The inclusion criteria were patients over 18 years of age, suspected myocarditis or dilated cardiomyopathy, accepted myocardial biopsy, and the detection of virus in the myocardial tissue.
Results.
In total, 10 studies met the inclusion criteria.
These studies included 1006 patients with suspected myocarditis or idiopathic heart disease for whom the primary endpoint was all-cause death, heart transplant, or re-hospitalization due to fatal arrhythmia and heart failure.
There was no significant difference in the prognosis of virus-positive and virus-negative patients with myocarditis or dilated cardiomyopathy confirmed by endomyocardial biopsy (EMB) [hazard ratio (HR) = 1.40, 95% confidence interval (CI) = 0.93–2.12, P=0.11].
However, virus-negative patients had a better prognosis following nonspecific treatment (HR = 1.40, 95% CI = 1.06–1.86, P=0.02) and right ventricular biopsy (HR = 2.08, 95% CI = 1.07–4.04, P=0.03).
Conclusions.
The presence of a virus did not worsen the long-term prognosis of patients with suspected myocarditis or dilated cardiomyopathy.
However, virus-positive patients who did not undergo specific treatment or who underwent right ventricular biopsy did have a worse prognosis.
Thus, the early diagnosis of the presence of viral infection in the myocardium will improve the prognosis of patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Wen-Hao& Guo, You-Sheng& Zhang, Dong-Hui& Zhang, Huan-Ji. 2019. Long-Term Prognosis of Suspected Myocarditis and Cardiomyopathy Associated with Viral Infection of the Myocardial Tissue: A Meta-Analysis of Cohort Studies. Cardiovascular Therapeutics،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1129244
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Wen-Hao…[et al.]. Long-Term Prognosis of Suspected Myocarditis and Cardiomyopathy Associated with Viral Infection of the Myocardial Tissue: A Meta-Analysis of Cohort Studies. Cardiovascular Therapeutics No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1129244
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Wen-Hao& Guo, You-Sheng& Zhang, Dong-Hui& Zhang, Huan-Ji. Long-Term Prognosis of Suspected Myocarditis and Cardiomyopathy Associated with Viral Infection of the Myocardial Tissue: A Meta-Analysis of Cohort Studies. Cardiovascular Therapeutics. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1129244
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129244
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر