Renal Dysfunction is a Risk Factor of Death after Gastric Endoscopic Submucosal Dissection in Elderly Patients Aged ≥80 Years
المؤلفون المشاركون
Maruoka, Daisuke
Arai, Makoto
Okimoto, Kenichiro
Ishigami, Hideaki
Taida, Takashi
Saito, Keiko
Nakagawa, Tomoo
Katsuno, Tatsuro
Kato, Naoya
Matsumura, Tomoaki
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
Endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is well accepted.
However, its adaptation for elderly patients is unclear.
This study aimed to investigate the prognosis and long-term outcomes of ESD for EGC in elderly patients aged ≥80 years by comparing their findings to the findings of patients aged <80 years.
Materials and Methods.
The study included 533 patients (632 lesions).
The patients were divided into an elderly group (age, ≥80 years; 108 patients; 128 lesions; mean age, 83.4 ± 2.7 years) and a nonelderly group (age, <80 years; 425 patients; 504 lesions; mean age, 69.6 ± 7.9 years).
We compared patient and lesion characteristics, overall survival (OS), and disease-specific survival (DSS) between the 2 groups retrospectively.
Multivariate analysis was performed to clarify the risk factors of death after ESD.
Results.
The rate of curative resection and adverse events was not significantly different between the groups.
The mean survival time periods with regard to OS/DSS in the elderly and nonelderly groups were 75.8 ± 5.9 and 122.8 ± 2.6 months (P<0.05)/120.0 ± 3.0 and 136.4 ± 0.6 months (not significant), respectively.
In the elderly group, eGFR <30 ml/min/1.73 m2 was an independent risk factor of death (hazard ratio = 5.32; 95% confidence interval = 1.39–20.5; P=0.015).
Conclusion.
ESD for EGC can be performed safely and can achieve high curability with good prognosis in elderly patients aged ≥80 years.
After ESD, close attention should be paid to elderly patients with severe chronic kidney disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Okimoto, Kenichiro& Arai, Makoto& Ishigami, Hideaki& Taida, Takashi& Saito, Keiko& Maruoka, Daisuke…[et al.]. 2019. Renal Dysfunction is a Risk Factor of Death after Gastric Endoscopic Submucosal Dissection in Elderly Patients Aged ≥80 Years. Canadian Journal of Gastroenterology and Hepatology،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1129897
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Okimoto, Kenichiro…[et al.]. Renal Dysfunction is a Risk Factor of Death after Gastric Endoscopic Submucosal Dissection in Elderly Patients Aged ≥80 Years. Canadian Journal of Gastroenterology and Hepatology No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1129897
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Okimoto, Kenichiro& Arai, Makoto& Ishigami, Hideaki& Taida, Takashi& Saito, Keiko& Maruoka, Daisuke…[et al.]. Renal Dysfunction is a Risk Factor of Death after Gastric Endoscopic Submucosal Dissection in Elderly Patients Aged ≥80 Years. Canadian Journal of Gastroenterology and Hepatology. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1129897
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129897
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر