Association between Hemoglobin Glycation Index and NAFLD in Chinese Nondiabetic Individuals
المؤلفون المشاركون
Hu, Di-Shuang
Zhu, Sheng-Hao
Li, Xu
Chen, Qin-Fen
Lin, Chun-Jing
Fang, Dan-Hong
Wu, Jian-Sheng
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
Limited studies have preliminarily identified a positive association between nonalcoholic fatty liver disease (NAFLD) and hemoglobin glycation index (HGI).
However, this association has not been fully established.
We aim to investigate the association between NAFLD and HGI in Chinese nondiabetic individuals and to construct a risk score based on HGI to predict a person’s risk of NAFLD.
Methods.
After strict exclusion criteria, 5,903 individuals were included in this retrospective cross-sectional study.
We randomly selected 1,967 subjects in the enrollment to obtain an equation of linear regression, which was used to calculate predicted HbA1c and drive HGI.
The other subjects were classified into four categories according to HGI level (≤−0.22, −0.21∼0.02, 0.03∼0.28, and ≥0.29).
All subjects retrospectively reviewed the baseline characteristics, laboratory examinations, and abdominal ultrasonography.
Results.
The prevalence of NAFLD in this population was 20.7%, which increases along with the growth of HGI levels (P<0.001).
Adjusted to multiple factors, this trend still remained significant (OR: 1.172 (95% CI, 1.074–1.279)).
The combined NAFLD risk score based on HGI resulted in an area under the receiver operator characteristic curve (AUROC) of 0.85 provided sensitivity, specificity, positive predictive value, and a negative predictive value for NAFLD of 84.4%, 71.3%, 65.0%, and 88.0%, respectively.
Conclusions.
NAFLD is independently associated with HGI levels in Chinese nondiabetic individuals.
And, NAFLD risk score may be used as one of the risk predictors of NAFLD in nondiabetic population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hu, Di-Shuang& Zhu, Sheng-Hao& Li, Xu& Chen, Qin-Fen& Lin, Chun-Jing& Fang, Dan-Hong…[et al.]. 2019. Association between Hemoglobin Glycation Index and NAFLD in Chinese Nondiabetic Individuals. Canadian Journal of Gastroenterology and Hepatology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129935
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hu, Di-Shuang…[et al.]. Association between Hemoglobin Glycation Index and NAFLD in Chinese Nondiabetic Individuals. Canadian Journal of Gastroenterology and Hepatology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1129935
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hu, Di-Shuang& Zhu, Sheng-Hao& Li, Xu& Chen, Qin-Fen& Lin, Chun-Jing& Fang, Dan-Hong…[et al.]. Association between Hemoglobin Glycation Index and NAFLD in Chinese Nondiabetic Individuals. Canadian Journal of Gastroenterology and Hepatology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129935
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129935
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر