The Prognostic Utility of Plasma NGAL Levels in ST Segment Elevation in Myocardial Infarction Patients
المؤلفون المشاركون
Avci, Ahmet
Ozturk, Bahadir
Demir, Kenan
Akyürek, Fikret
Altunkeser, Bulent Behlul
المصدر
Advances in Preventive Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Plasma neutrophil gelatinase-associated lipocalin (NGAL) levels in acute myocardial infarction (AMI) patients are markedly higher.
In addition, plasma NGAL levels were increased in patients with acute and chronic heart failure as a complication of myocardial infarction.
In this study, we investigated whether there is a difference between the prognostic use of plasma NGAL levels in ST-elevation myocardial infarction (STEMI) patients with preserved and reduced left ventricular ejection fraction (LVEF).
Methods.
235 consecutive STEMI patients were enrolled in the study.
Patients were divided into groups according to LVEF.
Plasma NGAL, troponin I, creatine kinase MB (CKMB), and C-reactive protein (CRP) were measured.
Finally, the study population examined with 34 reduced LVEF and 34 preserved LVEF consisted of a total of 68 patients (12 females; mean age, 61.5 ± 14.7).
All patients were followed up prospectively for 6 months.
This study group was divided into two subgroups as the patients who died (n = 14) and survived (n = 34), and plasma NGAL levels of the groups were compared.
Results.
The median of NGAL was 190.08 ng/ml.
Age, troponin I, CKMB, CRP, glomerular filtration rate, and creatinine were higher in reduced LVEF groups.
Plasma NGAL levels were also higher in reduced LVEF than in preserved LVEF, but statistically not significant (p=0.07).
Plasma NGAL levels were significantly higher in death patients than in survived patients (p<0.001).
In ROC curve analysis, the level to detect isolated cardiovascular mortality with a sensitivity of 86% and a specificity of 77% was 190 ng/mL for NGAL.
Conclusion.
Plasma NGAL levels can be used to predict cardiovascular mortality in STEMI patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Avci, Ahmet& Ozturk, Bahadir& Demir, Kenan& Akyürek, Fikret& Altunkeser, Bulent Behlul. 2020. The Prognostic Utility of Plasma NGAL Levels in ST Segment Elevation in Myocardial Infarction Patients. Advances in Preventive Medicine،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1130002
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Avci, Ahmet…[et al.]. The Prognostic Utility of Plasma NGAL Levels in ST Segment Elevation in Myocardial Infarction Patients. Advances in Preventive Medicine No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1130002
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Avci, Ahmet& Ozturk, Bahadir& Demir, Kenan& Akyürek, Fikret& Altunkeser, Bulent Behlul. The Prognostic Utility of Plasma NGAL Levels in ST Segment Elevation in Myocardial Infarction Patients. Advances in Preventive Medicine. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1130002
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130002
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر