Prevalence and Factors Associated with Multidrug-Resistant Tuberculosis (MDR-TB) among Presumptive MDR-TB Patients in Tigray Region, Northern Ethiopia
المؤلفون المشاركون
Kidane, Kibriti Mehari
Godefay, Hagos
Woldearegay, Tewolde Wubayehu
Araya, Tadele
Saravanan, Muthupandian
Asmelash, Tsehaye
Hailekiros, Haftamu
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-09
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Tuberculosis (TB) is one of the major public health problems.
There are alarming reports of increasing multidrug-resistant tuberculosis (MTR-TB) from various parts of the globe, including Ethiopia.
This study was designed to determine the prevalence and factors associated with MDR-TB among presumptive MDR-TB cases in Tigray Regional State, Ethiopia.
Methods.
A cross-sectional study was conducted in Tigray Regional State from 2015 to 2016.
Two hundred sputum samples were collected, transported, processed using 2% N-acetyl-L-cysteine-sodium hydroxide, and cultured in LJ medium.
Besides, the microscopic examination was performed after ZN staining.
Moreover, drug susceptibility test was done using molecular line probe assay.
Descriptive statistics and binary and multivariable logistic regression were done.
A statistical test was regarded as significant when the P value was <0.05.
Results.
The prevalence of MDR-TB was found to be 18.5%.
About one-fourth (26.5%) of the study participants had sputum smear positive for acid-fast bacilli (AFB).
TB culture was positive in 37% of the samples, and rifampicin mono-resistant cases accounted for 3.5% of the presumptive MDR-TB cases.
Three (1.5%) were new MDR-TB cases, while the rest had been treated previously for TB.
Most (63.5%) of the MDR-TB cases were from 15 to 44 years of age.
Age was associated with MDR-TB with a crude odds ratio of 1.06 (CI: 1.02–1.10) and adjusted odds ratio of 1.06 (CI: 1.00–1.11).
Conclusions.
The prevalence of MDR-TB was found to be high.
Preventive measures should be taken to prevent the transmission of MDR-TB in the community.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kidane, Kibriti Mehari& Asmelash, Tsehaye& Hailekiros, Haftamu& Woldearegay, Tewolde Wubayehu& Godefay, Hagos& Araya, Tadele…[et al.]. 2019. Prevalence and Factors Associated with Multidrug-Resistant Tuberculosis (MDR-TB) among Presumptive MDR-TB Patients in Tigray Region, Northern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1130037
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kidane, Kibriti Mehari…[et al.]. Prevalence and Factors Associated with Multidrug-Resistant Tuberculosis (MDR-TB) among Presumptive MDR-TB Patients in Tigray Region, Northern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1130037
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kidane, Kibriti Mehari& Asmelash, Tsehaye& Hailekiros, Haftamu& Woldearegay, Tewolde Wubayehu& Godefay, Hagos& Araya, Tadele…[et al.]. Prevalence and Factors Associated with Multidrug-Resistant Tuberculosis (MDR-TB) among Presumptive MDR-TB Patients in Tigray Region, Northern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1130037
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130037
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر