Prevalence, Antimicrobial Susceptibility Pattern of Bacterial Isolates, and Associated Factors of Urinary Tract Infections among HIV‐Positive Patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia
المؤلفون المشاركون
Marami, Dadi
Balakrishnan, Senthilkumar
Seyoum, Berhanu
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Urinary tract infection remains a major public health problem in developing countries, where there are limited health-care services.
Its prevalence is fueled by human immunodeficiency virus (HIV) infection.
The emergence of antimicrobial resistance is now widespread and poses a serious clinical threat.
This study investigated the prevalence, antimicrobial susceptibility pattern of bacterial isolates, and associated factors of urinary tract infections among HIV-positive adult patients.
A cross-sectional study was conducted among 350 randomly selected HIV-positive patients at Hiwot Fana Specialized University Hospital from February to March 2016.
Data were collected using a structured questionnaire.
Clean-catch midstream urine samples were collected aseptically and examined using the recommended culture methods.
Antimicrobial susceptibility testing was performed using the Kirby–Bauer disk diffusion technique.
Data were analyzed using Statistical Package for the Social Sciences version 21.0.
The logistic regression models were used to explore the predictors of the outcome.
A p value < 0.05 was considered statistically significant.
The overall prevalence of urinary tract infection was 18% (95% CI: 15.34–22.63).
Individuals with age 35–44 years (Adjusted odds ratio (AOR): 4.07; 95% CI: 1.09, 5.10), income less than 46.7 USD (AOR: 2.76; 95% CI: 1.15, 6.07), and a CD4+ count less than 200 cells/mm3 (AOR: 2.07; 95% CI: 1.15, 3.73) had higher odds of UTI.
Escherichia coli (38.1%), Klebsiella pneumoniae (23.8%), and Staphylococcus aureus (11.1%) were the predominant causes of urinary tract infection.
E.
coli was resistant to ampicillin (95.8%), ceftazidime (95.8%), cotrimoxazole (95.8%), amoxicillin (91.7%), ceftriaxone (87.5%), and tetracycline (87.2%).
Multidrug resistance was observed in 46% of the isolates.
The prevalence of urinary tract infection in this study was high compared to the previous reports in Ethiopia.
Age 35–44 years, income less than 46.7 USD, and a CD4+ count < 200 cells/mm3 increase the odds of urinary tract infection.
The most common isolates were E.
coli, K.
pneumoniae, and S.
aureus.
Almost half of the isolates were multidrug resistant.
Actions to help mitigate the further spread of resistance are urgently needed in the study area.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Marami, Dadi& Balakrishnan, Senthilkumar& Seyoum, Berhanu. 2019. Prevalence, Antimicrobial Susceptibility Pattern of Bacterial Isolates, and Associated Factors of Urinary Tract Infections among HIV‐Positive Patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1130100
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Marami, Dadi…[et al.]. Prevalence, Antimicrobial Susceptibility Pattern of Bacterial Isolates, and Associated Factors of Urinary Tract Infections among HIV‐Positive Patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1130100
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Marami, Dadi& Balakrishnan, Senthilkumar& Seyoum, Berhanu. Prevalence, Antimicrobial Susceptibility Pattern of Bacterial Isolates, and Associated Factors of Urinary Tract Infections among HIV‐Positive Patients at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1130100
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130100
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر