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Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection
المؤلفون المشاركون
Lv, Panpan
Zhao, Fang
Xu, Xiaoqin
Xu, Jun
Wang, Qiang
Zhao, Zhen
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-22
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
High-risk human papillomavirus (hr-HPV) infection is a necessary cause of cervical cancer.
However, other common lower genital tract microbes may increase hr-HPV infection and their related cervical cytopathy.
Methods.
To confirm this hypothesis, cervical brush and vaginal swab specimens were collected from 826 adult patients who were divided into the hr-HPV-positive group (254) and the negative group (572) by real-time PCR assay.
Cervical specimens were tested for Ureaplasma parvum (UP), Ureaplasma urealyticum (UU), and Chlamydia trachomatis (CT) using PCR analysis.
Vaginal secretion was detected for Trichomonas vaginalis (TV), Candida spp., and bacterial vaginosis (BV) with conventional assay.
Results.
Among hr-HPV-positive women, UP was found in 51.6%, UU in 15.4%, CT in 15.7%, Candida spp.
in 11.0%, TV in 3.1%, and BV in 20.5%.
In the hr-HPV-negative group, UP was positive in 36.2%, UU in 8.6%, CT in 4.0%, Candida spp.
in 12.4%, TV in 0.2%, and BV in 7.0%.
Multivariate logistic regression analysis with age-adjusted showed that UU (OR, 1.757), UP (OR, 1.804), CT (OR, 3.538), BV (OR, 3.020), and TV (OR, 14.109) were risk factors on hr-HPV infection (P<0.05).
Conclusion.
These microbes might induce cervical chronic inflammation that would damage the mucosal barrier and immune protection to promote the infection of hr-HPV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lv, Panpan& Zhao, Fang& Xu, Xiaoqin& Xu, Jun& Wang, Qiang& Zhao, Zhen. 2019. Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1130143
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lv, Panpan…[et al.]. Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1130143
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lv, Panpan& Zhao, Fang& Xu, Xiaoqin& Xu, Jun& Wang, Qiang& Zhao, Zhen. Correlation between Common Lower Genital Tract Microbes and High-Risk Human Papillomavirus Infection. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1130143
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130143
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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