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Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects
المؤلفون المشاركون
Bondar, Natalya P.
Lepeshko, Arina A.
Reshetnikov, Vasiliy V.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-09
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Stressful events in an early postnatal period have critical implications for the individual’s life and can increase later risk for psychiatric disorders.
The aim of this study was to investigate the influence of early-life stress on the social behavior of adult male and female mice.
C57Bl/6 mice were exposed to maternal separation (MS, 3 h once a day) or handling (HD, 15 min once a day) on postnatal day 2 through 14.
Adult male and female mice were tested for social behavior in the social interaction test and for individual behavior in the plus-maze and open-field tests.
Female mice exposed to maternal separation had increased social behavior and increased anxiety.
MS male mice had no changes in social behavior but had significantly disrupted individual behavior, including locomotor and exploratory activity.
Handling had positive effects on social behavior in males and females and decreased anxiety in males.
Our results support the hypothesis that brief separation of pups from their mothers (handling), which can be considered as moderate stress, may result in future positive changes in behavior.
Maternal separation has deleterious effects on individual behavior and significant sex-specific effects on social behavior.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bondar, Natalya P.& Lepeshko, Arina A.& Reshetnikov, Vasiliy V.. 2018. Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects. Behavioural Neurology،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1130147
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bondar, Natalya P.…[et al.]. Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects. Behavioural Neurology No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1130147
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bondar, Natalya P.& Lepeshko, Arina A.& Reshetnikov, Vasiliy V.. Effects of Early-Life Stress on Social and Anxiety-Like Behaviors in Adult Mice: Sex-Specific Effects. Behavioural Neurology. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1130147
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130147
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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