The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections
المؤلفون المشاركون
المصدر
Critical Care Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-22
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Invasive fungal infections (IFIs) have seen considerable increase in pediatric intensive care units over the past several decades.
IFIs are predominantly caused by Candida species, and candidemia is the third most common cause of healthcare-associated bloodstream infections (BSIs) in children.
IFIs are opportunistic infections that affect pediatric patients in critical care resulting in significant morbidity and mortality especially in those with a compromised immune system.
IFIs are the leading cause of death in children with comorbidities such as immunosuppression, and pediatric ICU admission has been shown to be an independent risk factor for mortality.
Management of IFI and fungal sepsis is broad and encompasses several key components that include prompt initiation of therapy and rapid source identification and control.
This study reviews important antifungals in the pediatric critical care setting including the pharmacologic properties, antifungal spectrum, adverse effects, and clinical uses of agents belonging to the four major classes of antifungals—the polyenes, azoles, echinocandins, and pyrimidine analogue flucytosine.
The polyenes and azoles are the most often used classes of antifungals.
The echinocandins are a relatively newer class of antifungal agents that offer excellent Candida activity and are currently recommended as the first-line therapy for invasive candidiasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kaushik, Ashlesha& Kest, Helen. 2018. The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections. Critical Care Research and Practice،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1130451
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kaushik, Ashlesha& Kest, Helen. The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections. Critical Care Research and Practice No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1130451
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kaushik, Ashlesha& Kest, Helen. The Role of Antifungals in Pediatric Critical Care Invasive Fungal Infections. Critical Care Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1130451
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130451
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر