Simulation Study on the Mass Transport Based on the Ciliated Dynamic System of the Respiratory Tract
المؤلفون المشاركون
Xu, Yuan-Qing
Zhu, Peng-Fei
Li, Xiang
Li, Ao
Liu, Yuan
Chen, Duan-Duan
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
To study the mass transport of mucociliary clearance of the human upper respiratory tract, a two-dimensional mass transport model based on the ciliated movement was established by using the immersed boundary-lattice Boltzmann method (IB-LBM).
In this model, different characteristics of the mucus layer (ML) and the periciliary liquid (PCL) were taken into account.
A virtual elastic membrane was introduced to divide the two layers dynamically.
All moving boundaries that were involved in the present simulation were modeled with the immersed boundary.
The Newtonian fluid was used to model the flow in PCL, and the viscoelastic fluid based on the Oldroyd-B model was used for the flow in ML; the two types of flow were both solved by the LBM framework.
Based on the model, the ML thickness, the cilia density, and the phase difference of adjacent cilia were regulated, respectively, to study the transport velocity of the ML.
In addition, the motion law of solid particles in PCL was also studied.
According to the results, four primary conclusions were drawn.
(1) At a given beating pattern, the increase of the ML thickness will decrease its transport velocity.
(2) Increasing the cilia density can promote the mean transport velocity of the ML.
(3) By raising the phase difference of adjacent cilia to a certain scope, the transport of ML can be accelerated.
(4) In PCL, particles initially located on the upper part of the cilia tend to migrate upward and then get close to the ML.
The above study can provide some reasonable explanations for the mechanism of the mucociliary clearance system, which is also helpful to the further understanding of the mass transport principle of the human upper respiratory tract.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Peng-Fei& Li, Xiang& Li, Ao& Liu, Yuan& Chen, Duan-Duan& Xu, Yuan-Qing. 2019. Simulation Study on the Mass Transport Based on the Ciliated Dynamic System of the Respiratory Tract. Computational and Mathematical Methods in Medicine،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1130628
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Peng-Fei…[et al.]. Simulation Study on the Mass Transport Based on the Ciliated Dynamic System of the Respiratory Tract. Computational and Mathematical Methods in Medicine No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1130628
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Peng-Fei& Li, Xiang& Li, Ao& Liu, Yuan& Chen, Duan-Duan& Xu, Yuan-Qing. Simulation Study on the Mass Transport Based on the Ciliated Dynamic System of the Respiratory Tract. Computational and Mathematical Methods in Medicine. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1130628
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130628
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر