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Prospective Multicenter Open-Label One-Arm Trial Investigating a Pumpkin Seed, Isoflavonoids, and Cranberry Mix in Lower Urinary Tract SymptomsBenign Prostatic Hyperplasia: A Pilot Study
المؤلفون المشاركون
Nemr, Elie
El Helou, Elie
Mjaess, Georges
Semaan, Albert
Chebel, Josselin Abi
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-13
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Phytotherapy for lower urinary tract symptoms (LUTSs) due to benign prostate hyperplasia (BPH) is progressively demanded by patients and trusted by physicians.
The aim was to assess the efficacy of a mix of pumpkin seed extract, soy germ isoflavonoids, and cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients.
Male patients aged ≥40 years, who had had mild to moderate LUTS for >6 months at screening, with no previous therapy or who are still symptomatic despite current use of alpha-blockers, were recruited.
Exclusion criteria were an IPSS >19 and an age >80 years.
The mixed compound was administered orally, daily, for 3 months.
Patients were evaluated by means of IPSS, urological quality of life (uQoL) index, and International Index of Erectile Function (IIEF-5) at 3 visits: baseline (visit 1), 30 days (visit 2), and 90 days after treatment (visit 3).
Among 163 screened patients, 128 patients (61.8 ± 9.9 years) were recruited.
IPSS improved from 15 (Q1 : 12–Q3 : 17) in visit 1, to 11 (Q1 : 8–Q3 : 14) in visit 2, and to 9 (Q1 : 6–Q3 : 12) in visit 3 (p<0.001).
uQoL improved from 4 (3–4) in visit 1, to 3 (2–3) in visit 2, and to 2 (1–2) in visit 3 (p<0.001).
The patients had an IIEF-5 score of 15 (12–18.7) in visit 1, 15 (12–18) in visit 2, and 17 (13–19) in visit 3 (p=0.99 visits 1 vs.
2, p=0.004 visits 2 vs.
3, and p=0.001 visits 1 vs.
3).
Treating mild to moderate LUTS/BPH patients with Novex® might therefore relieve symptoms, improve the quality of life, and have a mild beneficial effect on erectile function.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nemr, Elie& El Helou, Elie& Mjaess, Georges& Semaan, Albert& Chebel, Josselin Abi. 2020. Prospective Multicenter Open-Label One-Arm Trial Investigating a Pumpkin Seed, Isoflavonoids, and Cranberry Mix in Lower Urinary Tract SymptomsBenign Prostatic Hyperplasia: A Pilot Study. Advances in Urology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1130648
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nemr, Elie…[et al.]. Prospective Multicenter Open-Label One-Arm Trial Investigating a Pumpkin Seed, Isoflavonoids, and Cranberry Mix in Lower Urinary Tract SymptomsBenign Prostatic Hyperplasia: A Pilot Study. Advances in Urology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1130648
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nemr, Elie& El Helou, Elie& Mjaess, Georges& Semaan, Albert& Chebel, Josselin Abi. Prospective Multicenter Open-Label One-Arm Trial Investigating a Pumpkin Seed, Isoflavonoids, and Cranberry Mix in Lower Urinary Tract SymptomsBenign Prostatic Hyperplasia: A Pilot Study. Advances in Urology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1130648
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130648
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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