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Silver Nanoparticle Production by Ruta graveolens and Testing Its Safety, Bioactivity, Immune Modulation, Anticancer, and Insecticidal Potentials
المؤلفون المشاركون
Ghramh, Hamed A.
Ibrahim, Essam H.
Kilnay, Mona
Ahmad, Zubair
Alhag, Sadeq K.
Khan, Khalid Ali
Taha, Ramadan
Asiri, Fawziah M.
المصدر
Bioinorganic Chemistry and Applications
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-24
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Ruta graveolens, a plant belonging to the family Rutaceae, is traditionally used as a medicinal plant and a flavoring agent in food.
This work aimed to prepare silver nanoparticles (AgNPs) using the ethanol extract from R.
graveolens leaves and test different biological activities as well as insecticidal potentials in the extract and extract prepared AgNPs.
Dried and powdered R.
graveolens leaves were subjected to extraction using ethanol, and this extract was used to synthesize AgNPs.
AgNP synthesis was monitored by the change in color, UV spectrophotometry, and electron microscopy (scanning).
Fourier transform infrared (FT-IR) spectroscopy was used to monitor the functional groups in the extracts.
Immunological, physiological, anticancer, antibacterial, and insecticidal potentials of the extract and its prepared AgNPs were tested.
Results showed the ability of the leaf extract to synthesize.
SEM examination revealed a spherical shape of AgNPs with a size of 40–45 nm.
The extract contained many functional groups as indicated by FT-IR.
The extract alone inhibited the growth of normal rat splenic cells, while the extract containing AgNPs stimulated its growth.
Extract alone stimulated HeLa cell proliferation and inhibited HepG2 growth, while both cell line growth was inhibited by the extract containing AgNPs.
Both the extract and extract with AgNPs were safe on RBCs and did not cause any severe elevation in liver enzymes.
The extract alone and with AgNPs showed insecticidal activity against Culex pipiens.
Our findings suggest that the R.
graveolens leaf extract, alone or with AgNPs, is biologically safe on animal cells and has antibacterial, insecticidal, and immunomodulation potentials.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghramh, Hamed A.& Ibrahim, Essam H.& Kilnay, Mona& Ahmad, Zubair& Alhag, Sadeq K.& Khan, Khalid Ali…[et al.]. 2020. Silver Nanoparticle Production by Ruta graveolens and Testing Its Safety, Bioactivity, Immune Modulation, Anticancer, and Insecticidal Potentials. Bioinorganic Chemistry and Applications،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1130724
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghramh, Hamed A.…[et al.]. Silver Nanoparticle Production by Ruta graveolens and Testing Its Safety, Bioactivity, Immune Modulation, Anticancer, and Insecticidal Potentials. Bioinorganic Chemistry and Applications No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1130724
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghramh, Hamed A.& Ibrahim, Essam H.& Kilnay, Mona& Ahmad, Zubair& Alhag, Sadeq K.& Khan, Khalid Ali…[et al.]. Silver Nanoparticle Production by Ruta graveolens and Testing Its Safety, Bioactivity, Immune Modulation, Anticancer, and Insecticidal Potentials. Bioinorganic Chemistry and Applications. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1130724
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130724
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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