The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World
المؤلفون المشاركون
Church, Peter C.
Hyams, Jeffrey
Ruemmele, Frank
de Ridder, Lissy
Turner, Dan
Griffiths, Anne M.
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-12
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background and Aims.
Use of anti-TNF therapies varies internationally.
As an initiative of the international Pediatric IBD Network (PIBDNet), we compared global pediatric IBD anti-TNF practice patterns.
Methods.
Physicians were surveyed about anti-TNF use in Crohn’s disease (CD) and ulcerative colitis (UC).
Chi-squared, independent samples Mann–Whitney U, or related samples Wilcoxon signed rank tests were used to compare groups.
Results.
344 physicians treating pediatric IBD responded from 43 countries (54% North America, 29% Europe, 6% Oceania, 6% Asia, 3% Africa, and 2% South America).
Respondents treated a median 40 IBD patients.
CD was more commonly treated with anti-TNF than UC (40% vs.
10%, p<0.001).
North Americans more often used anti-TNF (median 50% vs.
30%, p<0.001) and before immunomodulator (80% vs.
35% CD, p<0.001; 76% vs.
43% steroid-dependent UC, p<0.001).
Anti-TNF monotherapy was more common in North America.
Anti-TNF in combination with methotrexate, instead of thiopurine, characterized North American practices.
North Americans more often continued immunomodulator indefinitely and less often adhered to standard infliximab induction dosing.
Access limitations were more common outside North America and Europe for both CD (67% vs.
31%, p<0.001) and UC (62% vs.
33%, p<0.001).
Conclusions.
Anti-TNF use in North America varies significantly from elsewhere.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Church, Peter C.& Hyams, Jeffrey& Ruemmele, Frank& de Ridder, Lissy& Turner, Dan& Griffiths, Anne M.. 2018. The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1130896
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Church, Peter C.…[et al.]. The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1130896
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Church, Peter C.& Hyams, Jeffrey& Ruemmele, Frank& de Ridder, Lissy& Turner, Dan& Griffiths, Anne M.. The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1130896
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130896
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر