The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases
المؤلفون المشاركون
Huynh, Hien Q.
Kluthe, Cheryl
Tsui, Jenkin
Spady, Donald
Carroll, Matthew
Wine, Eytan
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Medication nonadherence is a challenge in pediatric patients with inflammatory bowel diseases (IBD).
Poor adherence can result in disease flare-ups, disease complicationstherapy escalation, and the need for corticosteroids.
The aim was to determine if clinic visit frequency was associated with treatment adherence.
Methods.
A retrospective chart review of patients attending the Edmonton Pediatric IBD Clinic (EPIC) at the Stollery Children’s Hospital from January 2012 to December 2013 was completed.
Correlations were made between frequency of clinic visit, percentage of prescriptions filled, percentage of requisitioned blood work completed, rural or urban residence, and steroid-free remission status of patients for the 6 months after the chart review.
Results.
127 patients were reviewed with 82 patients diagnosed with Crohn’s disease (CD) and 46 with ulcerative colitis (UC) which included one IBD-Unclassified.
Mean age at diagnosis is 9.17 years and median duration of follow-up is 3.2 years.
Almost all patients on infliximab infusions received them “within window.” Immunomodulator median adherence rate was 88%.
5-ASA adherence was 82%.
A median of 67% of patients had blood work completed as requested.
Clinic visit frequency was not associated with adherence to blood work or to medications.
Duration of disease was the only independent factor found to be associated with a reduction in blood work and immunomodulator adherence (“OR 0.86 and 95% CI: 0.74–0.99” and “OR 0.82 and 95% CI: 0.71–0.97”) per year, respectively.
Patients who remained corticosteroid-free in the 6 months after the 2 years’ adherence review had an overall median medication adherence rate of 86% compared to only 53% for those who relapsed and required corticosteroids ( p = 0.01 ) .
Conclusion.
Clinic visit frequency was not associated with patient adherence to medications or blood work.
However, disease duration was found to be associated with medication adherence.
Adherent patients were more likely to remain in steroid-free remission.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kluthe, Cheryl& Tsui, Jenkin& Spady, Donald& Carroll, Matthew& Wine, Eytan& Huynh, Hien Q.. 2018. The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1130920
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kluthe, Cheryl…[et al.]. The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1130920
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kluthe, Cheryl& Tsui, Jenkin& Spady, Donald& Carroll, Matthew& Wine, Eytan& Huynh, Hien Q.. The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1130920
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130920
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر