Bacterial Infection and Predictors of Mortality in Patients with Autoimmune Liver Disease-Associated Acute-On-Chronic Liver Failure
المؤلفون المشاركون
Yang, Meifang
Zhang, Xuan
Hu, Jianhua
Zhao, Hong
Chen, Ping
Hao, Shaorui
Ma, Weihang
Gao, Hainv
Li, Lanjuan
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-28
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To date, few studies are available on autoimmune liver disease-associated acute-on-chronic liver failure (ACLF).
The aim of this study is to investigate bacterial infection and predictors of mortality in these patients.
Methods.
We retrospectively studied patients with autoimmune liver disease from August 2012 to August 2017.
Clinical data of the patients were retrieved for analysis.
Results.
There were 53 ACLF patients and 53 patients without ACLF in this study.
The ACLF group had a higher prevalence of complications (P<0.05).
The 28-day and 90-day mortality rates were also obviously high in patients with ACLF (38.3% and 74.5%, resp.) (P<0.05).
No predictor was significantly associated with 28-day and 90-day transplant-free mortality.
In 53ACLF patients, 40 (75.5%) patients showed bacterial infection.
ACLF patients with bacterial infection showed high Child-Pugh score, MELD score, CLIF-SOFA score, 28-day mortality, and 90-day mortality (P>0.05).
Moreover, C-reactive protein (CRP) using 12.15 mg/L cut-off value proved to be more accurate than procalcitonin in identifying patients with infection.
Conclusions.
Autoimmune liver disease-associated ACLF showed more complications and high mortality.
Bacterial infection patients displayed a more severe condition than those without infection.
Elevated CRP is an accurate marker for diagnosing bacterial infection in autoimmune liver disease-associated ACLF patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Xuan& Chen, Ping& Gao, Hainv& Hao, Shaorui& Yang, Meifang& Zhao, Hong…[et al.]. 2018. Bacterial Infection and Predictors of Mortality in Patients with Autoimmune Liver Disease-Associated Acute-On-Chronic Liver Failure. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1130949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Xuan…[et al.]. Bacterial Infection and Predictors of Mortality in Patients with Autoimmune Liver Disease-Associated Acute-On-Chronic Liver Failure. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1130949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Xuan& Chen, Ping& Gao, Hainv& Hao, Shaorui& Yang, Meifang& Zhao, Hong…[et al.]. Bacterial Infection and Predictors of Mortality in Patients with Autoimmune Liver Disease-Associated Acute-On-Chronic Liver Failure. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1130949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر