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A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy
المؤلفون المشاركون
Kobayashi, Takahiro
Tanaka, Yutaro
Nagai, Takashi
Kobayashi, Daichi
Akita, Hidetoshi
Moritoki, Yoshinobu
Okamura, T.
Yasui, Takahiro
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat.
Herein, we examined patients with PMGCTs who underwent multimodal treatment.
Methods.
We examined 6 patients (median age: 25 years, range: 19–27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015.
Three patients had seminomas, 2 patients had yolk sac tumors, and 1 patient had choriocarcinoma.
The median observation period was 32.5 months (range: 8–84 months).
Results.
Three of the 6 patients received initial operation followed by 3-4 courses of chemotherapy (bleomycin, etoposide, and cisplatin (BEP) or etoposide and cisplatin (EP)).
One patient developed multiple lung metastases 17 months after surgery; received salvage chemotherapy with vinblastine, ifosfamide, and cisplatin; and achieved complete remission.
The remaining 3 patients received initial BEP and EP chemotherapy.
Multiple lung metastases and supraclavicular lymph node metastases were detected in 2 of these patients at the initial diagnosis.
The patients underwent resections to remove residual tumor after treatment, and no viable tumor cells were found.
Conclusions.
Reliable diagnosis and immediate multimodal treatments are necessary for patients with PMGCTs.
The 6 patients treated in our hospital have never experienced recurrence after the multimodal treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tanaka, Yutaro& Okamura, T.& Nagai, Takashi& Kobayashi, Daichi& Kobayashi, Takahiro& Akita, Hidetoshi…[et al.]. 2017. A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy. Advances in Urology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1131018
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tanaka, Yutaro…[et al.]. A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy. Advances in Urology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1131018
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tanaka, Yutaro& Okamura, T.& Nagai, Takashi& Kobayashi, Daichi& Kobayashi, Takahiro& Akita, Hidetoshi…[et al.]. A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy. Advances in Urology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1131018
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131018
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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