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Distribution of Neuroendocrine Cells in the Transition Zone of the Prostate
المؤلفون المشاركون
Masumori, Naoya
Kyoda, Yuki
Ichihara, Koji
Hashimoto, Kohei
Kobayashi, Ko
Fukuta, Fumimasa
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
To evaluate the distribution of neuroendocrine (NE) cells which may influence the development of benign prostatic hyperplasia (BPH) in the transition zone (TZ).
Methods.
We reviewed specimens from 80 patients who underwent radical prostatectomy in our institution and evaluated the density of NE cells in the TZ.
They were histologically classified into 3 groups: those with no adenomatous nodule in the TZ (group A), those with small nodules with normal epithelium and stroma around them in the TZ (group B), and those with large nodules occupying the TZ (group C).
In the patients of group B, intra-adenoma (adenomatous nodules) and extra-adenoma (normal tissue) NE cells in the TZ were separately counted.
Results.
There were 22, 23, and 35 patients in groups A, B, and C, respectively.
The median density of NE cells in the TZ of group B patients, 2.80/mm2, was significantly higher than that of NE cells in group A, 1.43/mm2, and group C, 0.61/mm2 (p<0.001).
In group B, the median density of extra-adenoma NE cells was significantly higher than that of intra-adenoma.
Conclusions.
Many NE cells exist around small adenoma in the TZ.
NE cells may influence the initial growth of BPH in a paracrine fashion.
Trial Registration.
This study approved by our institutional review board was retrospectively registered (#272-14).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kyoda, Yuki& Ichihara, Koji& Hashimoto, Kohei& Kobayashi, Ko& Fukuta, Fumimasa& Masumori, Naoya. 2017. Distribution of Neuroendocrine Cells in the Transition Zone of the Prostate. Advances in Urology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1131044
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kyoda, Yuki…[et al.]. Distribution of Neuroendocrine Cells in the Transition Zone of the Prostate. Advances in Urology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1131044
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kyoda, Yuki& Ichihara, Koji& Hashimoto, Kohei& Kobayashi, Ko& Fukuta, Fumimasa& Masumori, Naoya. Distribution of Neuroendocrine Cells in the Transition Zone of the Prostate. Advances in Urology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1131044
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131044
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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