Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea
المؤلفون المشاركون
Lee, Kwangha
Kim, Won-Young
Jeong, Eun Suk
Kim, Insu
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
The aim of this pre- and postintervention cohort study was evaluating how effectively rapid pathogen identification with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) detected the causative organisms in sepsis.
Methods.
All consecutive adult patients who had bacteremia within 72 h of intensive care unit admission and met ≥2 quick Sequential Organ Failure Assessment criteria at intensive care unit admission were analyzed.
The patients whose microorganisms were identified via MALDI-TOF MS between March 2014 and February 2016 formed the postintervention group.
The patients whose microorganisms were identified by using conventional methods between March 2011 and February 2013 formed the preintervention group.
Results.
The postintervention group (n=58) had a shorter mean time from blood draw to receiving the antimicrobial susceptibility results than the preintervention group (n=40) (90.2 ± 32.1 vs.
108.7 ± 43.1 h; p=0.02).
The postintervention group was also more likely to have received active antimicrobial therapy by the time the susceptibility report became available (77% vs.
47%; p=0.005).
Its 28-day mortality was also lower (40% vs.
70%; p=0.003).
Univariate analysis showed that identification via MALDI-TOF MS (odds ratio, 0.28; 95% confidence interval, 0.12–0.66; p=0.004) and active therapy (odds ratio, 0.38; 95% confidence interval, 0.16–0.95; p=0.04) were associated with lower 28-day mortality.
Conclusion.
Rapid microorganism identification via MALDI-TOF MS followed by appropriate antimicrobial therapy may improve the clinical outcomes of patients with sepsis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Won-Young& Jeong, Eun Suk& Kim, Insu& Lee, Kwangha. 2018. Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131127
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Won-Young…[et al.]. Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1131127
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Won-Young& Jeong, Eun Suk& Kim, Insu& Lee, Kwangha. Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131127
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131127
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر