Determinants of Mortality in Patients with Nosocomial Acinetobacter baumannii Bacteremia in Southwest China: A Five-Year Case-Control Study
المؤلفون المشاركون
Yang, Shuangshuang
Sun, Jide
Wu, Xianan
Zhang, Liping
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
This study was aimed to identify the determinants of in-hospital mortality in Acinetobacter baumannii (A.
baumannii) bacteremia and to assess impact of carbapenem resistance on mortality.
Methods.
A five-year case-control study was conducted from January 2011 to December 2015 in a tertiary teaching hospital with 3200 beds, Southwest China.
Clinical outcomes and potential determinants of mortality in patients with nosocomial A.
baumannii bacteremia and carbapenem-resistant A.
baumannii (CRAB) bacteremia were evaluated using Cox and logistic regression analyses.
Results.
A total of 118 patients with nosocomial A.
baumannii bacteremia were included.
Seventy-one percent (84/118) of them had carbapenem-resistant A.
baumannii (CRAB) bacteremia.
The in-hospital mortality of nosocomial A.
baumannii bacteremia was 21.2%, and the attributable in-hospital mortality rate due to CRAB was 21.5%.
Significant difference of 30-day in-hospital mortality in the Kaplan–Meier curves was found between CRAB and CSAB groups (log-rank test, P=0.025).
The Cox regression analysis showed that patients with CRAB bacteremia had 2.72 times higher risk for 30-day in-hospital mortality than did those with carbapenem-susceptible A.
baumannii (CSAB) bacteremia (95% confidence intervals (CIs) 1.14–6.61, P=0.016).
The logistic regression analysis reported that mechanical ventilation and respiratory tract as origin of bacteremia were independent predictors of mortality among patients with nosocomial A.
baumannii bacteremia and CRAB bacteremia, while high APACHE II score on the day of bacteremia and multiple organ dysfunction syndromes (MODS) during hospitalization were independent predictors of mortality among patients with nosocomial A.
baumannii bacteremia but not CRAB bacteremia.
Conclusion.
It was the severity of illness (high APACHE II score and MODS) not carbapenem resistance that highlighted the mortality of patients with nosocomial A.
baumannii bacteremia.
The impact of mechanical ventilation on mortality suggested that respiratory dysfunction might prime the poor outcome.
Protection of respiratory function during the progression of nosocomial A.
baumannii bacteremia should be given more importance.
Early identification and intervention of patients with nosocomial A.
baumannii bacteremia in critical ill conditions were advocated.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Shuangshuang& Sun, Jide& Wu, Xianan& Zhang, Liping. 2018. Determinants of Mortality in Patients with Nosocomial Acinetobacter baumannii Bacteremia in Southwest China: A Five-Year Case-Control Study. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1131153
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Shuangshuang…[et al.]. Determinants of Mortality in Patients with Nosocomial Acinetobacter baumannii Bacteremia in Southwest China: A Five-Year Case-Control Study. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1131153
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Shuangshuang& Sun, Jide& Wu, Xianan& Zhang, Liping. Determinants of Mortality in Patients with Nosocomial Acinetobacter baumannii Bacteremia in Southwest China: A Five-Year Case-Control Study. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1131153
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131153
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر