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Clinical Outcomes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Infections with Susceptibilities among Levofloxacin, Cefepime, and Carbapenems
المؤلفون المشاركون
Walker, Kristy J.
Lee, Young R.
Klar, Amanda R.
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
Highly resistant Gram-negative bacterial infections are associated with high mortality.
Increasing resistance to standard therapy illustrates the need for alternatives when treating resistant organisms, especially extended-spectrum beta-lactamase- (ESBL-) producing Enterobacteriaceae.
Methods.
A retrospective chart review at a community hospital was performed.
Patients who developed ESBL-producing infections were included.
Patients less than eighteen years old, who were pregnant, or who were incarcerated were excluded.
The primary outcome was hospital mortality.
The secondary outcomes included intensive care unit (ICU) mortality, ICU length of stay, and hospital length of stay.
Results.
113 patients with ESBL-producing infections met the criteria for review.
Hospital mortality: carbapenem (16.6%), cefepime (0%), and levofloxacin (15.3%) (p=0.253).
ICU mortality: carbapenem (4.5%), cefepime, (0%), and levofloxacin (3.7%) (p=0.616).
Mean ICU and hospital length of stay: carbapenem (9.8 ± 16, 12.1 ± 1 days), cefepime (7.8 ± 6, 11.1 ± 10.5 days), and levofloxacin (5.4 ± 4.1, 11.1 ± 10.4 days) (p=0.805,0.685).
No predictors were clearly found between the source of infection and mortality.
Conclusion.
Cefepime or levofloxacin can be a potential alternative agent for infections with ESBL-producing Enterobacteriaceae, and larger clinical trials investigating these outcomes are warranted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Walker, Kristy J.& Lee, Young R.& Klar, Amanda R.. 2018. Clinical Outcomes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Infections with Susceptibilities among Levofloxacin, Cefepime, and Carbapenems. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131171
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Walker, Kristy J.…[et al.]. Clinical Outcomes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Infections with Susceptibilities among Levofloxacin, Cefepime, and Carbapenems. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1131171
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Walker, Kristy J.& Lee, Young R.& Klar, Amanda R.. Clinical Outcomes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Infections with Susceptibilities among Levofloxacin, Cefepime, and Carbapenems. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131171
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131171
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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