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Urolithiasis, Independent of Uric Acid, Increased Risk of Coronary Artery and Carotid Atherosclerosis: A Meta-Analysis of Observational Studies
المؤلفون المشاركون
Yan, Pijun
Xu, Ling
Luo, Wei
Zhou, Yao
Gao, Chenlin
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-20
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background and Aims.
Recent epidemiological evidence indicates an association between urolithiasis and atherosclerosis; however, results are incongruous.
Our aim is to summarize the association between urolithiasis and arteriosclerosis risk through a detailed meta-analysis.
Methods.
Relevant studies published before April 2019 were identified by searching OVID, EMBASE, PubMed, Web of Science database, and Cochrane Library.
The relationship between urolithiasis and the risk of atherosclerosis was assessed by using odds ratio (OR) values and the corresponding 95% confidence intervals (CIs), and the selection of fixed- or random-effects model based on heterogeneity.
Results.
The meta-analysis includes 8 observational studies that contained 70,716 samples.
Pooled results showed that urolithiasis was associated with an increased adjusted and unadjusted risk estimated for atherosclerosis (P=0.017 and P=0.014, respectively), especially in coronary artery and carotid atherosclerosis, which was associated with the outcome of CV disease.
Interestingly, when we merged the data from the vast majority of these samples (n = 65,751/70,716) with serum uric acid levels less than 6.0 mg/dl, it still showed that urolithiasis was associated with a higher risk of atherosclerosis (P<0.001) and with no evidence of heterogeneity (I2 = 0.0%, P=0.697).
Furthermore, we also found that renal calculi would increase the risk of moderate or severe atherosclerosis (P<0.001) and recurrent renal calculi were associated with the incidence of atherosclerosis (P=0.007).
Conclusions.
Urolithiasis is associated with an increased risk for atherosclerosis, especially in coronary artery and carotid atherosclerosis.
Urolithiasis may be another potential risk factor of atherosclerosis, which is independent of serum uric acid levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luo, Wei& Zhou, Yao& Gao, Chenlin& Yan, Pijun& Xu, Ling. 2020. Urolithiasis, Independent of Uric Acid, Increased Risk of Coronary Artery and Carotid Atherosclerosis: A Meta-Analysis of Observational Studies. BioMed Research International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1131384
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luo, Wei…[et al.]. Urolithiasis, Independent of Uric Acid, Increased Risk of Coronary Artery and Carotid Atherosclerosis: A Meta-Analysis of Observational Studies. BioMed Research International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1131384
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luo, Wei& Zhou, Yao& Gao, Chenlin& Yan, Pijun& Xu, Ling. Urolithiasis, Independent of Uric Acid, Increased Risk of Coronary Artery and Carotid Atherosclerosis: A Meta-Analysis of Observational Studies. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1131384
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131384
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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