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Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review
المؤلفون المشاركون
Heena, Humariya
AlFayyad, Isamme
Nofal, Abdullah
Abdelmoety, Doaa A.
Abu-Shaheen, Amani
Almatary, Abdulrahman
Alsheef, Mohammed
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-29
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Background.
Thalassemia has a burden on the healthcare systems of many countries.
About 56000 conceptions result in thalassemia, globally.
Objective.
To assess the epidemiological profile of thalassemia in the Gulf Cooperation Council (GCC) countries.
Methods.
A systematic search was conducted in MEDLINE/PubMed (National Library of Medicine), CINAHL, and Embase.
Relevant observational studies reporting the epidemiology of thalassemia among the GCC population were selected.
Data on the prevalence, frequency, and complications of thalassemia were extracted.
The quality of the retrieved studies was assessed according to the Newcastle–Ottawa Quality Assessment Scale.
Results.
Eighteen studies (14 cross-sectional studies, two retrospective observational studies, and two retrospective analysis) with a total of 3343042 participants were included in this systematic review.
Of the 18 studies, 11 studies were conducted in Saudi Arabia, two in the Kingdom of Bahrain, one in Kuwait, three in the United Arab Emirates (UAE), and one in Qatar.
The prevalence of thalassemia among children below five years of age ranged from 0.25% to 33%, while it was 0.9% in children above five years and from 0.035% to 43.3% among adult thalassemia patients.
The most-reported risk factors were consanguineous marriage and high-risk marriage.
There was a lack of data regarding mortality rates in thalassemia.
Conclusions.
Despite the premarital screening and genetic counseling (PMSGC) program for thalassemia, the incidence of high-risk couple marriages in GCC countries cannot be effectively diminished.
This study suggested that the PMSGC program should adopt more attention for the high-risk areas, to enhance the level of consciousness about the hemoglobinopathy diseases and the consequences of consanguinity among the at-risk couple.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abu-Shaheen, Amani& Heena, Humariya& Nofal, Abdullah& Abdelmoety, Doaa A.& Almatary, Abdulrahman& Alsheef, Mohammed…[et al.]. 2020. Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review. BioMed Research International،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1131699
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abu-Shaheen, Amani…[et al.]. Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review. BioMed Research International No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1131699
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abu-Shaheen, Amani& Heena, Humariya& Nofal, Abdullah& Abdelmoety, Doaa A.& Almatary, Abdulrahman& Alsheef, Mohammed…[et al.]. Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1131699
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131699
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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