Analyzing Knowledge Retrieval Impairments Associated with Alzheimer’s Disease Using Network Analyses

المؤلفون المشاركون

Zemla, Jeffrey C.
Austerweil, Joseph L.

المصدر

Complexity

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-05-02

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الفلسفة

الملخص EN

A defining characteristic of Alzheimer’s disease is difficulty in retrieving semantic memories, or memories encoding facts and knowledge.

While it has been suggested that this impairment is caused by a degradation of the semantic store, the precise ways in which the semantic store is degraded are not well understood.

Using a longitudinal corpus of semantic fluency data (listing of items in a category), we derive semantic network representations of patients with Alzheimer’s disease and of healthy controls.

We contrast our network-based approach with analyzing fluency data with the standard method of counting the total number of items and perseverations in fluency data.

We find that the networks of Alzheimer’s patients are more connected and that those connections are more randomly distributed than the connections in networks of healthy individuals.

These results suggest that the semantic memory impairment of Alzheimer’s patients can be modeled through the inclusion of spurious associations between unrelated concepts in the semantic store.

We also find that information from our network analysis of fluency data improves prediction of patient diagnosis compared to traditional measures of the semantic fluency task.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zemla, Jeffrey C.& Austerweil, Joseph L.. 2019. Analyzing Knowledge Retrieval Impairments Associated with Alzheimer’s Disease Using Network Analyses. Complexity،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1131746

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zemla, Jeffrey C.& Austerweil, Joseph L.. Analyzing Knowledge Retrieval Impairments Associated with Alzheimer’s Disease Using Network Analyses. Complexity No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1131746

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zemla, Jeffrey C.& Austerweil, Joseph L.. Analyzing Knowledge Retrieval Impairments Associated with Alzheimer’s Disease Using Network Analyses. Complexity. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1131746

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1131746