Comparative Safety and Efficacy of Left Atrial Appendage Occlusion with the Watchman Device and Amplatzer Cardiac Plug: Results of the Russian National Registry
المؤلفون المشاركون
Davtyan, Karapet
Simonyan, Georgiy
Topchyan, Arpi
Kalemberg, Andrey
Romanov, Alexander
Shabanov, Vitaliy
Lebedev, Dmitriy
Gureev, Sergey
Miller, Yulia
Merkulov, Evgeniy
Pevzner, Dmitry
Mozgovoy, Pavel
Ufimtsev, Vladimir
Boytsov, Sergey
Drapkina, Oksana
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
This multicenter, prospective registry evaluated the comparative safety and efficacy of left atrial appendage occlusion (LAAO) using the Watchman device (WD) and the Amplatzer Cardiac Plug (ACP) in patients with nonvalvular atrial fibrillation (NVAF) in real-world clinical practice in Russia.
Methods.
The study included data from 200 consecutive NVAF patients (66.8±7.8 years, 44.5% female, median CHA2DS2VASc 4, median HAS-BLED 3) who had undergone LAAO implantation using WD (n=108) or ACP (n=92) from September 2015 to December 2017 in 5 medical centers in Russia.
The primary safety endpoint was the procedure-related major adverse events, and the primary efficacy endpoint was the composite of thromboembolic events, device thrombosis, hemorrhagic events, and unexplained death during the 12-month follow-up.
Results.
Successful LAAO was performed in all 92 (100%) patients with ACP and 105 (97.2%) with WD (p=0.053).
At 12 months, primary safety endpoint occurred in 6.5% of patients in the ACP group with no events in the WD group (6.5% vs.
0%, p=0.008).
During the 12-month follow-up, the primary efficacy endpoint has occurred in 8.3% of patients in the WD group (n=9) and 1.1% of patients in the ACP group (n=1) (p=0.016).
Conclusions.
In this multicenter prospective registry, LAA closure with the WD was associated with significantly higher thromboembolic events rate in NVAF patients.
Patients, receiving the ACP, had more procedure-related major adverse events.
However, further multicenter studies are necessary to evaluate these findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Davtyan, Karapet& Simonyan, Georgiy& Topchyan, Arpi& Kalemberg, Andrey& Romanov, Alexander& Shabanov, Vitaliy…[et al.]. 2020. Comparative Safety and Efficacy of Left Atrial Appendage Occlusion with the Watchman Device and Amplatzer Cardiac Plug: Results of the Russian National Registry. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1132451
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Davtyan, Karapet…[et al.]. Comparative Safety and Efficacy of Left Atrial Appendage Occlusion with the Watchman Device and Amplatzer Cardiac Plug: Results of the Russian National Registry. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1132451
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Davtyan, Karapet& Simonyan, Georgiy& Topchyan, Arpi& Kalemberg, Andrey& Romanov, Alexander& Shabanov, Vitaliy…[et al.]. Comparative Safety and Efficacy of Left Atrial Appendage Occlusion with the Watchman Device and Amplatzer Cardiac Plug: Results of the Russian National Registry. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1132451
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132451
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر