Hemangiopericytoma: Incidence, Treatment, and Prognosis Analysis Based on SEER Database
المؤلفون المشاركون
Wang, Kewei
Mei, Fei
Wu, Sisi
Tan, Zui
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-03
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Hemangiopericytomas are rare tumors derived from pericytes surrounding the blood vessels.
The clinicopathological characteristics and prognosis of hemangiopericytoma patients remain mostly unknown.
In this retrospective cohort study, we assessed the clinicopathological characteristics of hemangiopericytoma patients, as well as the clinical usefulness of different treatment modalities.
Material and Methods.
We collected the clinicopathological data (between 1975 and 2016) of hemangiopericytoma and hemangioendothelioma patients from the Surveillance, Epidemiology, and End Results (SEER) database.
Incidence, treatment, and patient prognosis were assessed.
Results.
Data from 1474 patients were analyzed in our study cohort (hemangiopericytoma: n=1243; hemangioendothelioma: n=231).
The incidence of hemangiopericytoma in 2016 was 0.060 per 100,000 individuals.
The overall survival (OS) and cancer-specific survival (CSS) did not differ between patients with hemangioendothelioma and those with hemangiopericytoma (P=0.721, P=0.544).
The tumor grade had no effect on the OS of hemangiopericytoma patients.
Multivariate analysis revealed the clinical usefulness of surgery in hemangiopericytoma patients (HR=0.15, 95% confidence interval: 0.05-0.41, P<0.001).
In contrast, radiotherapy did not improve OS (P=0.497) or CSS (P=0.584), and chemotherapy worsened patient survival (P<0.001).
Additionally, the combination of surgery and radiotherapy had a similar effect with surgery alone on hemangiopericytoma patient survival (OS: P=0.900; CSS: P=0.156).
Surgery plus chemotherapy provided a worse clinical benefit than surgery alone (P<0.001).
Conclusions.
Our findings suggested that hemangiopericytoma had a similar prognosis with hemangioendothelioma.
Surgery was the only effective treatment that provided survival benefits in hemangiopericytoma patients, while the clinical usefulness of adjuvant chemotherapy or radiotherapy was limited.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Kewei& Mei, Fei& Wu, Sisi& Tan, Zui. 2020. Hemangiopericytoma: Incidence, Treatment, and Prognosis Analysis Based on SEER Database. BioMed Research International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1132520
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Kewei…[et al.]. Hemangiopericytoma: Incidence, Treatment, and Prognosis Analysis Based on SEER Database. BioMed Research International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1132520
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Kewei& Mei, Fei& Wu, Sisi& Tan, Zui. Hemangiopericytoma: Incidence, Treatment, and Prognosis Analysis Based on SEER Database. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1132520
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132520
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر