Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens’ Minisatellite 33.15-Tagged Transcript pAKT-45 Variants
المؤلفون المشاركون
Shahbaaz, Mohd
Al-Samghan, Awad Saeed
Malik, Arshi
Afaq, Sarah
Alwabli, Afaf S.
Ahmad, Irfan
Hussien, Mostafa A.
Zubair, Mohammad
Fatima, Farha
Begum, Shamina
Alzahrani, Othman
Tarique, Mohammed
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The spermatozoa are transcriptionally dormant entities which have been recognized to be an archive of mRNA, coding for a variety of functionally crucial cellular proteins.
This significant repository of mRNA is predicted to be associated with early embryogenesis and postfertilization.
The mRNA transcripts which are tagged with minisatellites have been involved in the regulation of the gene functions as well as their organization.
However, very little information is available regarding the expression of the transcripts tagged with minisatellites in spermatozoa.
Therefore, in order to understand the functions and the conformational behavior of the proteins expressed from these minisatellite-tagged transcripts, we have performed a detailed in silico analysis using the sequences of the transcripts.
The protein predicted from KF274549 showed the functionalities similar to uncharacterized C4orf26 proteins, while that obtained from KF274557 predicted to be a metallophosphoesterase.
Furthermore, the structural folds in the structure of these predicted proteins were analyzed by using the homology modeling and their conformational behaviors in the explicit water conditions were analyzed by using the techniques of Molecular Dynamics (MD) simulations.
This detailed analysis will facilitate the understanding of these proteins in the spermatozoon region and can be used for uncovering other attributes of the metabolic network.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shahbaaz, Mohd& Al-Samghan, Awad Saeed& Malik, Arshi& Afaq, Sarah& Alwabli, Afaf S.& Ahmad, Irfan…[et al.]. 2020. Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens’ Minisatellite 33.15-Tagged Transcript pAKT-45 Variants. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132592
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shahbaaz, Mohd…[et al.]. Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens’ Minisatellite 33.15-Tagged Transcript pAKT-45 Variants. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1132592
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shahbaaz, Mohd& Al-Samghan, Awad Saeed& Malik, Arshi& Afaq, Sarah& Alwabli, Afaf S.& Ahmad, Irfan…[et al.]. Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens’ Minisatellite 33.15-Tagged Transcript pAKT-45 Variants. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132592
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132592
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر