Trace Level Detection of Bisphenol A Analogues and Parabens by LC-MSMS in Human Plasma from Malaysians
المؤلفون المشاركون
Wiraagni, Idha Arfianti
Rashid, Rusdi Abdul
Haron, Didi Erwandi bin Mohamad
Mohd, Mustafa Ali
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
In this study, a novel LC-MS/MS method was designed using a simple extraction procedure that was scientifically developed to capture the most relevant bisphenol A (BPA) analogues (BPB, BPF, BPS, and BPAF) and parabens (propylparaben, ethylparaben, butylparaben, and methylparaben) in human plasma.
The LC-MS/MS method was validated using US FDA guidelines, and all validation requirements were satisfactory.
This is the method that allows for the detection of plasma bisphenols and parabens in one run and is also the fastest BPA analogue and paraben detection technique for human plasma.
The method was used to analyze samples from 150 healthy volunteers from Malaysia who enrolled in the study.
No BPB was detected in any of the volunteers; however, 99.3% were positive for BPF.
Only 24% and 10.7% of volunteers were positive for BPAF and BPS, respectively.
A high percentage of volunteers were negative for propylparaben, ethylparaben, butylparaben, and methylparaben (56%, 68%, 86.7%, and 83.3%, respectively).
These results suggest that persons in Malaysia are exposed to different BPA analogues and parabens, from both the daily use of products (cosmetic and plastic products) and the environment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wiraagni, Idha Arfianti& Mohd, Mustafa Ali& Rashid, Rusdi Abdul& Haron, Didi Erwandi bin Mohamad. 2020. Trace Level Detection of Bisphenol A Analogues and Parabens by LC-MSMS in Human Plasma from Malaysians. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1132604
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wiraagni, Idha Arfianti…[et al.]. Trace Level Detection of Bisphenol A Analogues and Parabens by LC-MSMS in Human Plasma from Malaysians. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1132604
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wiraagni, Idha Arfianti& Mohd, Mustafa Ali& Rashid, Rusdi Abdul& Haron, Didi Erwandi bin Mohamad. Trace Level Detection of Bisphenol A Analogues and Parabens by LC-MSMS in Human Plasma from Malaysians. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1132604
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132604
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر