Predictors of Outcome in Clinically Diagnosed Viral Encephalitis Patients: A 5-Year Prospective Study
المؤلفون المشاركون
Feng, Guibo
Zhou, Lunqin
Li, Feng
Hu, Yida
Wang, Xuefeng
Tian, Xin
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Viral encephalitis is the most common infectious disease of the central nervous system and is associated with high morbidity, mortality, and disability.
The objective of this study was to analyze the clinical characteristics, auxiliary examinations, therapeutic management, and outcomes of patients clinically diagnosed with viral encephalitis and identify the outcome predictors.
Methods.
We conducted a prospective observational study by collecting information from patients clinically diagnosed with viral encephalitis at the First Affiliated Hospital of Chongqing Medical University and Yongchuan Hospital of Chongqing Medical University from January 2013 to December 2018.
Univariate and multivariate analyses were performed to identify factors that influenced good patient outcomes (mRS<3) and poor patient outcomes (mRS≥3) at discharge.
Results.
In total, 216 patients were enrolled in the study.
The multivariate analysis suggested that the following factors were associated with a poor outcome: Glasgow Coma Scale (GCS) score (OR 0.154, 95% CI (0.078-0.302), and P<0.001), focal neurological deficits (OR 9.403, 95% CI (1.581-55.928), and P=0.014), and total length of hospital stay (OR 1.119, 95% CI (1.002-1.250), and P=0.045).
However, neurological intensive care unit (NICU) treatment, status epilepticus, and abnormal electroencephalogram (EEG) findings did not influence the prognosis of patients.
Conclusion.
Our study suggests that low GCS scores at admission, focal neurological deficits at admission, and a prolonged total hospital stay are predictors of a poor outcome at discharge in clinically diagnosed viral encephalitis patients.
Whether early and effective neurological rehabilitation can improve the prognosis of viral encephalitis patients with focal neurological deficits remains to be confirmed in further studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Feng, Guibo& Zhou, Lunqin& Li, Feng& Hu, Yida& Wang, Xuefeng& Tian, Xin. 2020. Predictors of Outcome in Clinically Diagnosed Viral Encephalitis Patients: A 5-Year Prospective Study. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132747
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Feng, Guibo…[et al.]. Predictors of Outcome in Clinically Diagnosed Viral Encephalitis Patients: A 5-Year Prospective Study. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1132747
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Feng, Guibo& Zhou, Lunqin& Li, Feng& Hu, Yida& Wang, Xuefeng& Tian, Xin. Predictors of Outcome in Clinically Diagnosed Viral Encephalitis Patients: A 5-Year Prospective Study. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132747
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132747
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر