Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019
المؤلفون المشاركون
Ye, Jishi
Chen, Jingli
Li, Hui
Xia, Zhongyuan
Yan, Hong
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-12
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Since the first reports of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in December 2019 in Wuhan, China, the virus has spread to other parts of China and across the world.
Although a few studies have assessed the clinical course of coronavirus disease 2019 (COVID-19), the changes in clinical characteristics during disease progression remain unclear.
Methods.
We retrospectively analyzed the clinical characteristics of 62 patients who died from COVID-19 at the Central Hospital of Wuhan between January 26 and February 17, 2020.
We compared the clinical features on admission and at the last follow-up before death.
Results.
Of the 62 patients with COVID-19, 41 (66%) patients were male, and 21 (34%) were female.
The median age was 72 years (interquartile range (IQR), 54-88), and 45 (72.5%) patients had preexisting conditions.
The median time from symptom onset to the first visit at the clinic was three days, while the median time from symptom onset to death was 18.5 days.
During disease progression, the amounts of arterial gases worsened, and liver, renal, and heart dysfunction was observed.
Due to the cytokine storm, infection-related biomarkers, including lactic acid, C-reactive protein, and interleukine-6, gradually worsened during hospitalization.
Conclusion.
Our findings suggest that during hospitalization, many COVID-19 patients experienced multiple organ dysfunction and cytokine storm.
The time from symptom onset to death was only 18.5 days, highlighting the disease’s rapid progression.
The better understanding of the clinical changes during disease progression might provide further insight into the COVID-19 pathophysiology.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Jingli& Ye, Jishi& Li, Hui& Xia, Zhongyuan& Yan, Hong. 2020. Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019. BioMed Research International،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1133119
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Jingli…[et al.]. Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019. BioMed Research International No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1133119
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Jingli& Ye, Jishi& Li, Hui& Xia, Zhongyuan& Yan, Hong. Changes in the Clinical Characteristics of 62 Patients Who Died from Coronavirus Disease 2019. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1133119
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1133119
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر