Application of Acellular Tissue Matrix for Enhancement of Weak Abdominal Wall in Animal Model
المؤلفون المشاركون
Hu, San-yuan
Wang, Minggang
Yang, Shuo
Cao, Zhen
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-12
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Abdominal wall weakness occurs when the strength of muscle decreases due to physiological reason or iatrogenic injury.
However, the treatment of this disease is complicated.
Aim.
To study the therapeutic effect of acellular tissue matrix (ACTM), compared with the polypropylene mesh.
Methods.
An abdominal wall weakness model was established in rabbits through motor nerves cutting.
The polypropylene mesh and ACTM were implanted in the left and right abdomen sides, respectively.
Mechanical testing of abdominal wall muscle and histology and scanning electron microscopy (SEM) evaluation of abdominal tissue explants were performed.
Results.
In animal model establishment, the abdominal length of healthy and weakened abdominal wall was 17.0 ± 0.7 cm and 19.0 ± 1.2 cm, respectively (P=0.022), and the weak abdominal wall group showed a significant decrease of 1.116 ± 0.221 MPa in tensile stress (P<0.001) and 9.126 ± 2.073% in tensile strain (P<0.001).
In materials implantation experiment, compared with polypropylene group, ACTM group decreased 2.409 ± 0.806 MPa after 24 weeks (P<0.001) and 2.319 ± 0.486 MPa after 48 weeks (P<0.001) in tensile stress and increased 15.259% after 24 weeks (P<0.001) and 15.845% after 48 weeks (P<0.001) remarkably in tensile strain.
Conclusion.
The abdominal wall weakness model in rabbits was successfully established.
ACTM is a promising biological material to be possibly further applied in clinical surgery in patients with abdominal wall weakness.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Minggang& Yang, Shuo& Cao, Zhen& Hu, San-yuan. 2020. Application of Acellular Tissue Matrix for Enhancement of Weak Abdominal Wall in Animal Model. BioMed Research International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1133197
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Minggang…[et al.]. Application of Acellular Tissue Matrix for Enhancement of Weak Abdominal Wall in Animal Model. BioMed Research International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1133197
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Minggang& Yang, Shuo& Cao, Zhen& Hu, San-yuan. Application of Acellular Tissue Matrix for Enhancement of Weak Abdominal Wall in Animal Model. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1133197
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1133197
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر