Comparison of Clinical Features and Treatment Outcome in Benign and Malignant Lacrimal Sac Tumors

المؤلفون المشاركون

Tsai, Chieh-Chih
Liu, Catherine Jui-Ling
Kuo, Che-Yuan
Kao, Shu-Ching
Hsu, Wen-Ming

المصدر

BioMed Research International

العدد

المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-4، 4ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2020-01-31

دولة النشر

مصر

عدد الصفحات

4

التخصصات الرئيسية

الطب البشري

الملخص EN

Purpose.

To compare the clinical characteristics and treatment outcome between benign and malignant lacrimal sac tumors.

Methods.

We retrospectively reviewed the medical records of all patients with pathologically confirmed lacrimal sac lesions from 1995 to 2018 in a tertiary medical center.

Results.

Among 65 eligible cases, 46 (70.8%) were benign lacrimal sac tumors and 19 (29.2%) were malignant lacrimal sac tumors.

Secondary malignancy from nasal or paranasal cancer accounted for 47% of malignant lacrimal sac tumors.

The patient’s mean age at the time of diagnosis was 60 years in the benign group and 48 years in the malignant group (p=0.03).

The most common presenting symptoms were a palpable lump/mass and epiphora in both groups.

Palpable mass extending above the medial canthal tendon was noted in 9% of the benign group and in 74% of the malignant group, respectively (p<0.001).

Bloody tears were noted in 5% of the benign group and in 20% of the malignant group (p=0.21).

In the malignant group, 10 (52.6%) were primary tumors and 9 (47.4%) were secondary tumors.

The primary sites of the metastatic tumor to the lacrimal sac area were mostly from neighboring paranasal sinuses and nasal cavity.

The recurrence rate was higher in patients with malignant tumors, as compared to the benign tumors (42% and 6%, respectively, p=0.001).

The metastatic rate was 47% and the mortality rate was 53% in malignant lacrimal sac tumors.

Conclusion.

Although benign and malignant lacrimal sac tumors may present similar initial symptoms, timely diagnosis and intervention for malignant lacrimal sac lesions are important because they tend to be infiltrating tumors with a poor outcome.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kuo, Che-Yuan& Tsai, Chieh-Chih& Kao, Shu-Ching& Hsu, Wen-Ming& Liu, Catherine Jui-Ling. 2020. Comparison of Clinical Features and Treatment Outcome in Benign and Malignant Lacrimal Sac Tumors. BioMed Research International،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1133283

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kuo, Che-Yuan…[et al.]. Comparison of Clinical Features and Treatment Outcome in Benign and Malignant Lacrimal Sac Tumors. BioMed Research International No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1133283

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kuo, Che-Yuan& Tsai, Chieh-Chih& Kao, Shu-Ching& Hsu, Wen-Ming& Liu, Catherine Jui-Ling. Comparison of Clinical Features and Treatment Outcome in Benign and Malignant Lacrimal Sac Tumors. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1133283

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1133283