Acute Deterioration of Pulmonary Arterial Hypertension (PAH) in a Patient with Neurofibromatosis Type 1 (NF1)
المؤلفون المشاركون
Tanaka, Seiya
Kawahara, Fuko
Miyamoto, Taro
Tsurusaki, Satoshi
Sanuki, Yoshihito
Ozumi, Kiyoshi
Harada, Takashi
Tasaki, Hiromi
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-22
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
A 56-year-old woman was diagnosed as having chronic obstructive pulmonary disease with heavy smoking.
Mild pulmonary hypertension (mean pulmonary arterial pressure: 31 mmHg) was detected at the first visit.
She was diagnosed with pulmonary hypertension due to pulmonary disease and medicated only with bronchodilators.
Simultaneous, multiple freckling in the trunk of her body and café au lait macules in her back with some cutaneous neurofibromas were also detected.
A plastic surgeon removed one of the neurofibromas and pathologically diagnosed it as neurofibromatosis type 1 (NF1).
We finally rediagnosed her with pulmonary hypertension with unclear and/or multifactorial factors when she deteriorated 1 year after being treated only with bronchodilators.
We then administrated upfront combination therapy with macitentan and tadalafil.
Mean pulmonary arterial pressure rapidly improved.
Learning Objective.
Pulmonary arterial hypertension (PAH) in neurofibromatosis type 1 (NF1) can occur due to lung disease or due to certain involvement of pulmonary arteries, or a combination of both.
Increased awareness of PAH in NF1 is very important for patients survival.
The current therapeutic strategy is almost identical to that of idiopathic PAH; however, there is no clinical evidence.
Insights gained from clinical experiences should help identify promising novel therapeutic approaches in NF1-PAH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tanaka, Seiya& Kawahara, Fuko& Miyamoto, Taro& Tsurusaki, Satoshi& Sanuki, Yoshihito& Ozumi, Kiyoshi…[et al.]. 2019. Acute Deterioration of Pulmonary Arterial Hypertension (PAH) in a Patient with Neurofibromatosis Type 1 (NF1). Case Reports in Cardiology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1133636
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tanaka, Seiya…[et al.]. Acute Deterioration of Pulmonary Arterial Hypertension (PAH) in a Patient with Neurofibromatosis Type 1 (NF1). Case Reports in Cardiology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1133636
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tanaka, Seiya& Kawahara, Fuko& Miyamoto, Taro& Tsurusaki, Satoshi& Sanuki, Yoshihito& Ozumi, Kiyoshi…[et al.]. Acute Deterioration of Pulmonary Arterial Hypertension (PAH) in a Patient with Neurofibromatosis Type 1 (NF1). Case Reports in Cardiology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1133636
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1133636
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر