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Endophytic Actinobacteria Associated with Dracaena cochinchinensis Lour.: Isolation, Diversity, and Their Cytotoxic Activities
المؤلفون المشاركون
Manikprabhu, Deene
Salam, Nimaichand
Khieu, Thi-Nhan
Liu, Min-Jiao
Vu, Thu-Trang
Chu-Ky, Son
Quach, Ngoc-Tung
Phi, Quyet-Tien
Fontana, Angélique
Sarter, Samira
Li, Wen-Jun
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-06
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Dracaena cochinchinensis Lour.
is an ethnomedicinally important plant used in traditional Chinese medicine known as dragon’s blood.
Excessive utilization of the plant for extraction of dragon’s blood had resulted in the destruction of the important niche.
During a study to provide a sustainable way of utilizing the resources, the endophytic Actinobacteria associated with the plant were explored for potential utilization of their medicinal properties.
Three hundred and four endophytic Actinobacteria belonging to the genera Streptomyces, Nocardiopsis, Brevibacterium, Microbacterium, Tsukamurella, Arthrobacter, Brachybacterium, Nocardia, Rhodococcus, Kocuria, Nocardioides, and Pseudonocardia were isolated from different tissues of D.
cochinchinensis Lour.
Of these, 17 strains having antimicrobial and anthracyclines-producing activities were further selected for screening of antifungal and cytotoxic activities against two human cancer cell lines, MCF-7 and Hep G2.
Ten of these selected endophytic Actinobacteria showed antifungal activities against at least one of the fungal pathogens, of which three strains exhibited cytotoxic activities with IC50-values ranging between 3 and 33 μg·mL−1.
Frequencies for the presence of biosynthetic genes, polyketide synthase- (PKS-) I, PKS-II, and nonribosomal peptide synthetase (NRPS) among these 17 selected bioactive Actinobacteria were 29.4%, 70.6%, and 23.5%, respectively.
The results indicated that the medicinal plant D.
cochinchinensis Lour.
is a good niche of biologically important metabolites-producing Actinobacteria.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salam, Nimaichand& Khieu, Thi-Nhan& Liu, Min-Jiao& Vu, Thu-Trang& Chu-Ky, Son& Quach, Ngoc-Tung…[et al.]. 2017. Endophytic Actinobacteria Associated with Dracaena cochinchinensis Lour.: Isolation, Diversity, and Their Cytotoxic Activities. BioMed Research International،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1133830
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salam, Nimaichand…[et al.]. Endophytic Actinobacteria Associated with Dracaena cochinchinensis Lour.: Isolation, Diversity, and Their Cytotoxic Activities. BioMed Research International No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1133830
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salam, Nimaichand& Khieu, Thi-Nhan& Liu, Min-Jiao& Vu, Thu-Trang& Chu-Ky, Son& Quach, Ngoc-Tung…[et al.]. Endophytic Actinobacteria Associated with Dracaena cochinchinensis Lour.: Isolation, Diversity, and Their Cytotoxic Activities. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1133830
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1133830
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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