CNS Metastases from Bone and Soft Tissue Sarcomas in Children, Adolescents, and Young Adults: Are They Really So Rare?
المؤلفون المشاركون
Bekiesinska-Figatowska, Monika
Duczkowska, Agnieszka
Duczkowski, Marek
Bragoszewska, Hanna
Romaniuk-Doroszewska, Anna
Iwanowska, Beata
Szkudlinska-Pawlak, Sylwia
Madzik, Jaroslaw
Bilska, Katarzyna
Raciborska, Anna
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-24
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
To check whether primary involvement of brain/spinal cord by bone/soft tissue sarcomas’ metastases in children is as rare as described and to present various morphological forms of bone/soft tissue sarcomas’ CNS metastases.
Methods.
Patients with first diagnosis in 1999–2014 treated at single center were included with whole course of disease evaluation.
Brain/spinal canal magnetic resonance imaging (MRI)/computed tomography were performed in cases suspicious for CNS metastases.
Extension from skull/vertebral column metastases was excluded.
Results.
550 patients were included.
MRI revealed CNS metastases in 19 patients (incidence 3.45%), 14 boys, aged 5–22 years.
There were 12/250 osteosarcoma cases, 2/200 Ewing’s sarcoma, 1/50 chondrosarcoma, 3/49 rhabdomyosarcoma (RMS), and 1/1 malignant mesenchymoma.
There were 10 single metastases and 7 cases of multiple ones; in 2 RMS cases only leptomeningeal spread in brain and spinal cord was found.
Calcified metastases were found in 3 patients and hemorrhagic in 4.
In one RMS patient there were numerous solid, cystic, hemorrhagic lesions and leptomeningeal spread.
Conclusions.
CNS metastases are rare and late in children with bone/soft tissue sarcomas, although in our material more frequent (3.45%) than in other reports (0.7%).
Hematogenous spread to brain and hemorrhagic and calcified lesions dominated in osteosarcoma.
Ewing sarcoma tended to metastasize to skull bones.
Soft tissue sarcomas presented various morphological forms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bekiesinska-Figatowska, Monika& Duczkowska, Agnieszka& Duczkowski, Marek& Bragoszewska, Hanna& Romaniuk-Doroszewska, Anna& Iwanowska, Beata…[et al.]. 2017. CNS Metastases from Bone and Soft Tissue Sarcomas in Children, Adolescents, and Young Adults: Are They Really So Rare?. BioMed Research International،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1133935
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bekiesinska-Figatowska, Monika…[et al.]. CNS Metastases from Bone and Soft Tissue Sarcomas in Children, Adolescents, and Young Adults: Are They Really So Rare?. BioMed Research International No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1133935
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bekiesinska-Figatowska, Monika& Duczkowska, Agnieszka& Duczkowski, Marek& Bragoszewska, Hanna& Romaniuk-Doroszewska, Anna& Iwanowska, Beata…[et al.]. CNS Metastases from Bone and Soft Tissue Sarcomas in Children, Adolescents, and Young Adults: Are They Really So Rare?. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1133935
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1133935
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر