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Stable Colonization of Orally Administered Lactobacillus casei SY13 Alters the Gut Microbiota
المؤلفون المشاركون
Yue, Yuanchun
Xu, Xiaoxi
Yang, Baoyu
Lu, Jing
Zhang, Shuwen
Liu, Liu
Nassar, Khaled
Zhang, Cai
Zhang, Min
Pang, Xiaoyang
Lv, Jiaping
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-13
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The gut microbiota plays an important role in intestinal health.
Probiotics such as Lactobacillus are known to regulate gut microbes and prevent diseases.
However, most of them are unable to colonize their stability in hosts’ intestinal tracts.
In this study, we investigated the ability of Lactobacillus casei SY13 (SY13) to colonize the intestinal tract of BALB/c mice, after its oral administration for a short-term (once for a day) and long-term (once daily for 27 days) duration.
Furthermore, we also evaluated the influence of its administration on the gut microbial structure and diversity in mice.
Male BALB/c mice were gavaged with 108 colony-forming units (CFU) of SY13, and TaqMan-MGB probe and Illumina MiSeq sequencing were performed to assess the colonization ability and bacterial community structure in the cecum contents.
The results showed that long-term treatment with SY13 enhanced its ability to form a colony in the intestine tract in contrast to the short-term treatment group, whose colony was retained for only 3 days.
Oral administration of SY13 also significantly enhanced the gut microbial diversity.
Short-term treatment with SY13 (SSY13) elevated Firmicutes and diminished Bacteroidetes phyla compared with long-term treatment (LSY13) and controls.
The findings laid the foundation for the study of probiotic colonization ability and improvement of microbiota for the prevention of gut diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yue, Yuanchun& Xu, Xiaoxi& Yang, Baoyu& Lu, Jing& Zhang, Shuwen& Liu, Liu…[et al.]. 2020. Stable Colonization of Orally Administered Lactobacillus casei SY13 Alters the Gut Microbiota. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134633
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yue, Yuanchun…[et al.]. Stable Colonization of Orally Administered Lactobacillus casei SY13 Alters the Gut Microbiota. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1134633
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yue, Yuanchun& Xu, Xiaoxi& Yang, Baoyu& Lu, Jing& Zhang, Shuwen& Liu, Liu…[et al.]. Stable Colonization of Orally Administered Lactobacillus casei SY13 Alters the Gut Microbiota. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134633
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1134633
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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