Activity of Fosfomycin- and Daptomycin-Containing Bone Cement on Selected Bacterial Species Being Associated with Orthopedic Infections
المؤلفون المشاركون
Hofpeter, Kevin
Sculean, Anton
Ender, Claudia
Klimas, Susann
Vogt, Sebastian
Nietzsche, Sandor
Eick, Sigrun
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-06
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The purpose of this study was to determine activity of fosfomycin/gentamicin and daptomycin/gentamicin-containing PMMA bone-cement against Staphylococcus aureus (MRSA, MSSA), Staphylococcus epidermidis, Enterococcus faecium (VRE), and E.
coli (ESBL; only fosfomycin).
Test specimens of the bone cement were formed and bacteria in two concentrations were added one time or repeatedly up to 96 h.
All fosfomycin-containing cement killed ultimately all MSSA, Staphylococcus epidermidis, and E.
coli within 24 h; growth of MRSA was suppressed up to 48 h.
Activity of daptomycin-containing cement depended on the concentration; the highest concentrated bone cement used (1.5 g daptomycin/40 g of powder) was active against all one-time added bacteria.
When bacteria were added repeatedly to fosfomycin-containing cement, growth was suppressed up to 96 h and that of MRSA and VRE only up to 24 h.
The highest concentration of daptomycin suppressed the growth of repeated added bacteria up to 48 h (VRE) until 96 h (MSSA, MRSA).
In conclusion, PMMA bone cement with 1.5 g of daptomycin and 0.5 g of gentamicin may be an alternative in treatment of periprosthetic infections caused by Gram-positive bacteria.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Eick, Sigrun& Hofpeter, Kevin& Sculean, Anton& Ender, Claudia& Klimas, Susann& Vogt, Sebastian…[et al.]. 2017. Activity of Fosfomycin- and Daptomycin-Containing Bone Cement on Selected Bacterial Species Being Associated with Orthopedic Infections. BioMed Research International،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1134640
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Eick, Sigrun…[et al.]. Activity of Fosfomycin- and Daptomycin-Containing Bone Cement on Selected Bacterial Species Being Associated with Orthopedic Infections. BioMed Research International No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1134640
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Eick, Sigrun& Hofpeter, Kevin& Sculean, Anton& Ender, Claudia& Klimas, Susann& Vogt, Sebastian…[et al.]. Activity of Fosfomycin- and Daptomycin-Containing Bone Cement on Selected Bacterial Species Being Associated with Orthopedic Infections. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1134640
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1134640
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر