Patient-Reported Outcomes of Arsenic-Related Skin Lesions in China
المؤلفون المشاركون
Li, Yajia
Jing, Danrong
Xiao, Yi
Huang, Xiaoyan
Shen, Minxue
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
Previous studies confirmed that chronic arsenic exposure could lead to pigmentary changes and hyperkeratosis.
However, skin health-related quality of life (HRQoL) among people under lifetime arsenic exposure remains underappreciated.
Our study is aimed at investigating several patient-reported outcomes in a population under chronic arsenic exposure.
Patients and Methods.
A cross-sectional study was conducted in communities in Shimen, China.
Dermatologists performed skin examinations for participants.
Patient-reported outcomes (PROs) included HRQoL, itch, sleep quality, and symptoms of anxiety and depression.
The Dermatology Life Quality Index (DLQI) was used to measure skin HRQoL.
The numerical rating scale (NRS) was used to measure the intensity of itching.
Sleep disturbance was measured by Pittsburgh Sleep Quality Index (PSQI).
Anxiety and depression were measured by two-item Generalized Anxiety Disorder (GAD-2) and Patient Health Questionnaire (PHQ-2), respectively.
Results.
A total of 464 participants suffering from arsenic-related skin lesions finished the assessment of DLQI.
Pigmentary changes and arsenical keratosis were not associated with the patient-reported outcomes except PHQ-2.
Hair arsenic exceeding 1 μg/g was associated with higher itch NRS and DLQI (P<0.05).
Itch NRS (adjusted β=0.80, 95% CI: 0.70–0.90, P<0.01) and hair arsenic concentration (adjusted β=0.12, 95% CI: 0.01–0.24, P<0.05) were independently associated with the DLQI.
Conclusion.
HRQoL, sleep quality, and mental wellbeing are impaired in residents under chronic arsenic exposure.
Itching and hair arsenic are independent risk factors for impaired HRQoL.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yajia& Jing, Danrong& Xiao, Yi& Huang, Xiaoyan& Shen, Minxue. 2020. Patient-Reported Outcomes of Arsenic-Related Skin Lesions in China. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1135624
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yajia…[et al.]. Patient-Reported Outcomes of Arsenic-Related Skin Lesions in China. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1135624
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yajia& Jing, Danrong& Xiao, Yi& Huang, Xiaoyan& Shen, Minxue. Patient-Reported Outcomes of Arsenic-Related Skin Lesions in China. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1135624
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135624
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر