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Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment
المؤلفون المشاركون
Dai, Shu-Qin
Wang, Xueping
Mao, Min-jie
Wei, Xiao-li
Sheng, Hui
Li, Xiao-hui
Liu, Yi-jun
Xing, Shan
Huang, Qi
Liu, Wan-li
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
The pretreatment albumin and globulin ratio (AGR) was an inflammation-associated factor which was related to the overall survival in various malignancies.
The aim of this study was to evaluate the prognostic value of AGR in patients with gastric cancer.
Method.
This retrospective study included 862 cases pathologically diagnosed with gastric cancer.
All patients were randomly divided into the testing group (431 cases) and validation group (431 cases).
The relationships of AGR with clinicopathologic characteristics and prognosis were analyzed by Kaplan-Meier and Cox regression methods.
Results.
In the testing group, the median overall survival was 26.90 months and the cutoff value of AGR was 1.50 based on R language.
Kaplan-Meier analysis showed that lower AGR was correlated with poorer overall survival.
Multivariate analysis demonstrated that AGR was an independent prognostic factor for overall survival (HR: 0.584, 95% CI = 0.351–0.973, and p = 0.039).
In the validation group, the median overall survival was 24.10 months.
Lower AGR (≤1.50) also had a significantly poorer overall survival by Kaplan-Meier analysis.
According to multivariate analysis, the AGR was also confirmed to be an independent prognostic factor for overall survival (HR: 0.578, 95% CI = 0.373–0.897, and p = 0.015).
Conclusions.
Our study suggested that the pretreatment AGR could be a prognostic biomarker for overall survival in patients with gastric cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mao, Min-jie& Wei, Xiao-li& Sheng, Hui& Wang, Xueping& Li, Xiao-hui& Liu, Yi-jun…[et al.]. 2017. Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1135696
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mao, Min-jie…[et al.]. Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1135696
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mao, Min-jie& Wei, Xiao-li& Sheng, Hui& Wang, Xueping& Li, Xiao-hui& Liu, Yi-jun…[et al.]. Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1135696
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135696
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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