Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma in the Same Patient as a Collision Tumour
المؤلفون المشاركون
Dikbas, Oguz
Duman, Aslihan Alpaslan
Guvendi, Gulname Findik
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-12
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Aim.
Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are two different types of thyroid carcinoma with significant different clinical and histological findings.
Their coexistence in the same patient is a very rare event which demands different clinical approach.
Case Report.
We report a case with concurrent MTC and PTC in the same thyroid having characteristics of a collision tumour.
A 35-year-old patient has admitted to endocrinology outpatient department with complaint of pain in the neck.
Physical examination revealed 2 cm nodule on the thyroid right lobe.
Serum thyroid hormone levels were within normal range.
Ultrasonography revealed a 23x15 mm hypoechoic nodule with micro calcifications and cystic areas on the right lobe.
Preoperative serum calcitonin was 2 pg/ml (0-11.5).
PTK 1.7 cm and MTK 1.8 cm in the same thyroid with healthy tissue in between them were detected on pathological examination.
RET gene mutation was negative.
She has been followed up to now without any evidence of disease.
Conclusion.
This is a collision tumour since lesions with features of MTC and PTC were detected in two different locations and separated by normal thyroid tissue.
Germline point mutation of the RET gene had a potential role in the development of both MTC and PTC.
On the other side, familial concurrent MTC and PTC without RET gene mutation was also published.
Both RET and BRAF genes had a role in the development of the medullary and papillary collision tumours.
We do not know the presence of BRAF gene mutation in this case report yet.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dikbas, Oguz& Duman, Aslihan Alpaslan& Guvendi, Gulname Findik. 2019. Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma in the Same Patient as a Collision Tumour. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135722
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dikbas, Oguz…[et al.]. Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma in the Same Patient as a Collision Tumour. Case Reports in Endocrinology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1135722
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dikbas, Oguz& Duman, Aslihan Alpaslan& Guvendi, Gulname Findik. Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma in the Same Patient as a Collision Tumour. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135722
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135722
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر