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Adult Nesidioblastosis in Chronic Kidney Disease
المؤلفون المشاركون
Lozano-Melendez, Eduardo
Aguilar-Soto, Mercedes
Graniel-Palafox, Luis Eugenio
Ceceña-Martínez, Laura Elena
Valdez-Ortiz, Rafael
Solis-Jimenez, Fabio
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Context.
Nesidioblastosis is a rare cause of hyperinsulinemic hypoglycemia in adults.
The diagnosis is further complicated in patients with kidney failure, since impaired renal function can cause hypoglycemia by itself and diagnostic criteria for this clinical scenario have not been developed yet.
Case Description.
We present the case report of a 36-year-old patient with end stage chronic kidney disease who presented to the emergency department because of hypoglycemia.
However, the patient’s hypoglycemia did not respond well to medical treatment; the diagnosis of hyperinsulinemic hypoglycemia was made due to the presence of inappropriately high levels of insulin, proinsulin, and C-peptide during an episode of hypoglycemia.
Imaging studies were performed without any conclusive findings; so selective intra-arterial pancreatic stimulation with hepatic venous sampling (SACTS) was done.
Based on the results of this study the patient was referred for subtotal pancreatectomy.
Classic criteria for the diagnosis of insulinoma with SACTS required a 2-fold increase in insulin levels but newer criteria suggest thresholds that are useful in the differential diagnosis of insulinoma and nesidioblastosis.
In our patient, the former criteria were positive; however, the new criteria were not compatible with insulinoma but with nesidioblastosis, which was the final histopathological diagnosis.
Conclusion.
This seems to be the first case report of a patient with end stage chronic kidney disease and nesidioblastosis, as well as the first case of hyperinsulinemic hypoglycemia in the context of kidney failure diagnosed by SACTS.
We consider this method to be very useful in patients with renal impairment because peripancreatic insulin levels do not depend on the renal function.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lozano-Melendez, Eduardo& Aguilar-Soto, Mercedes& Graniel-Palafox, Luis Eugenio& Ceceña-Martínez, Laura Elena& Valdez-Ortiz, Rafael& Solis-Jimenez, Fabio. 2019. Adult Nesidioblastosis in Chronic Kidney Disease. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1135814
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lozano-Melendez, Eduardo…[et al.]. Adult Nesidioblastosis in Chronic Kidney Disease. Case Reports in Endocrinology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1135814
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lozano-Melendez, Eduardo& Aguilar-Soto, Mercedes& Graniel-Palafox, Luis Eugenio& Ceceña-Martínez, Laura Elena& Valdez-Ortiz, Rafael& Solis-Jimenez, Fabio. Adult Nesidioblastosis in Chronic Kidney Disease. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1135814
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135814
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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