A Case of Severe Acute Kidney Injury Exacerbated by Canagliflozin in a Patient with Type 2 Diabetes
المؤلفون المشاركون
Hassani-Ardakania, Kimya
Lipman, Mark L.
Laporta, Denny
Yu, Oriana Hoi Yun
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-04
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Sodium glucose cotransport (SGLT)-2 inhibitors are the newest class of antihyperglycemic agents used as second- or third-line treatment in the management of type 2 diabetes.
Although the use of SGLT-2 inhibitors has not been shown to cause nephrotoxicity, there have been case reports of SGLT-2 inhibitor use being associated with acute kidney injury.
Case Presentation.
A 72-year-old woman with a history of type 2 diabetes and no known chronic renal insufficiency presented to the emergency room with a 3-day history of nausea, vomiting, and increased somnolence.
She was found to have potassium level of 7.4 (normal: 3.5-5.5) mmol/L and a markedly elevated creatinine level at 1154 (normal: 45-95) μmol/L.
Imaging of the abdomen and pelvis did not reveal any findings of obstruction.
Urine microscopy showed many granular casts.
In the absence of other causes for her clinical presentation, the patient was diagnosed with acute kidney injury secondary to ischemic acute tubular necrosis, with canagliflozin use likely an important contributing factor.
Conclusions.
Physicians should inform patients to stop the use of SGLT-2 inhibitors when patients are unable to maintain hydration or during acute illness.
Use of SGLT-2 inhibitors in managing type 2 diabetes should be done with caution among more vulnerable populations, including individuals with cognitive impairment and the elderly.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hassani-Ardakania, Kimya& Lipman, Mark L.& Laporta, Denny& Yu, Oriana Hoi Yun. 2019. A Case of Severe Acute Kidney Injury Exacerbated by Canagliflozin in a Patient with Type 2 Diabetes. Case Reports in Endocrinology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135838
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hassani-Ardakania, Kimya…[et al.]. A Case of Severe Acute Kidney Injury Exacerbated by Canagliflozin in a Patient with Type 2 Diabetes. Case Reports in Endocrinology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1135838
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hassani-Ardakania, Kimya& Lipman, Mark L.& Laporta, Denny& Yu, Oriana Hoi Yun. A Case of Severe Acute Kidney Injury Exacerbated by Canagliflozin in a Patient with Type 2 Diabetes. Case Reports in Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1135838
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135838
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر