A Selection of Trauma Scores Might Not Correlate with Coagulation Factor Activity following Multiple Injuries: A Retrospective Observational Study from a Level 1 Trauma Center
المؤلفون المشاركون
Dudda, Marcel
Burggraf, Manuel
Polan, Christina
Meyer, Heinz-Lothar
Müller, Roman Maximilian
Reinecke, Felix
Kauther, Max Daniel
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Loss and dilution of coagulation factors have been observed following multiple trauma.
Timely recognition of reduced clotting factor activity might facilitate therapeutic action to restore normal coagulation function.
This study investigates the potential role of some well-known trauma scores in predicting coagulation factor activity after multiple injuries.
A dataset comprising the coagulation factor activities of 68 multiply injured adult patients was analyzed.
The following trauma scores were evaluated: AIS, ISS, NISS, GCS, RTS, TRISS, RISC, and TASH score.
To investigate the effect of trauma severity with respect to a single anatomic injury location, two groups according to the AIS (<3 vs.
≥3 points) were formed.
Differences between these two groups were analyzed for five different body regions (head, thorax, abdomen, pelvis, extremities) using the Mann–Whitney U-test.
Spearman’s rank correlation coefficient rho was calculated to reveal possible relationships between trauma scores and clotting factor activities.
The analysis showed clearly reduced clotting factor activities with a significant reduction of FII (83 vs.
50%; P=.021) and FV (83 vs.
46%; P=.008) for relevant (AIS≥3 points) pelvic injuries.
In contrast, traumatic brain injury according to the AIS head or the GCS does not appear to lead to a significant decrease in coagulation factor activities.
Furthermore, the other scores studied show at best a fair correlation with coagulation factor activity.
In this context, the RTS score seems to be the most suitable.
Additionally, the predictive value of the TASH score, which was specifically developed to predict the need for mass transfusion, was also limited in this study.
We would like to explicitly point out that this is not a criticism of the trauma scores, since they were developed in a completely different context.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Burggraf, Manuel& Polan, Christina& Meyer, Heinz-Lothar& Müller, Roman Maximilian& Reinecke, Felix& Dudda, Marcel…[et al.]. 2020. A Selection of Trauma Scores Might Not Correlate with Coagulation Factor Activity following Multiple Injuries: A Retrospective Observational Study from a Level 1 Trauma Center. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136129
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Burggraf, Manuel…[et al.]. A Selection of Trauma Scores Might Not Correlate with Coagulation Factor Activity following Multiple Injuries: A Retrospective Observational Study from a Level 1 Trauma Center. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1136129
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Burggraf, Manuel& Polan, Christina& Meyer, Heinz-Lothar& Müller, Roman Maximilian& Reinecke, Felix& Dudda, Marcel…[et al.]. A Selection of Trauma Scores Might Not Correlate with Coagulation Factor Activity following Multiple Injuries: A Retrospective Observational Study from a Level 1 Trauma Center. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136129
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136129
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر