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Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature
المؤلفون المشاركون
Kemm, Matthew H.
Manly, Cory D.
Hoang, Thanh D.
Mai, Vinh Q.
Shakir, Mohamed K. M.
المصدر
Case Reports in Gastrointestinal Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We report a patient with multiple endocrine neoplasia type 1 with pancreatic polypeptide (PP) secreting subcentimeter pancreatic neuroendocrine tumors (pNETs) treated with octreotide and review the current literature that pertains to the management of these patients.
Clinical data, laboratory results, and imaging were reviewed.
A literature search was performed in PUBMED using combinations of the terms “multiple endocrine neoplasia type 1,” “somatostatin,” octreotide,” “pancreatic polypeptide,” and “pancreatic tumor.” Relevant references were selected and reviewed.
A 43-year-old male with a history of MEN1 and multiple subcentimeter neuroendocrine tumors with elevation of PP was treated with octreotide therapy leading to a reduction and normalization of PP levels.
The patient tolerated octreotide therapy but self-discontinued octreotide after 24 months with a rise in PP levels off therapy.
Tumors remained stable in size through 40 months of imaging follow-up.
In patients with MEN1 and subcentimeter pNETs, octreotide therapy is well tolerated and can lead to a significant drop in PP levels with no change in lesion size.
There is insufficient data to suggest long-term benefit with octreotide therapy but it may be considered versus standard conservative management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kemm, Matthew H.& Manly, Cory D.& Hoang, Thanh D.& Mai, Vinh Q.& Shakir, Mohamed K. M.. 2019. Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1136324
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kemm, Matthew H.…[et al.]. Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1136324
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kemm, Matthew H.& Manly, Cory D.& Hoang, Thanh D.& Mai, Vinh Q.& Shakir, Mohamed K. M.. Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature. Case Reports in Gastrointestinal Medicine. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1136324
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136324
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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