Staphylococcal Enterotoxins and Toxic Shock Syndrome Toxin-1 and Their Association among Bacteremic and Infective Endocarditis Patients in Egypt
المؤلفون المشاركون
Eltayeb, Wafaa N.
Elsherif, Heba M.
Helal, Zeinab H.
El-Ansary, Mona R.
Fahmy, Zeinab A.
Radwan, Sahar
Aboshanab, Khaled M.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Purpose.
Infective endocarditis (IE) is a major complication in patients with bacteremia of Staphylococcus (S.) aureus infection.
Our aim was to determine the association of the major Staphylococcal superantigens (SAgs), including Staphylococcal enterotoxins (SEs) and toxic shock syndrome toxin-1 (TSST-1), among hospitalized patients diagnosed with bacteremia and those with IE.
Methods.
This study was conducted on 88 patients; of these, 84 (95.5%) had two positive blood cultures.
Eighteen out of the 84 patients (21.4%) were diagnosed based on the modified Duke criteria by a cardiologist to have IE.
The recovered isolates were screened phenotypically using ELISA followed by molecular analysis of sea, seb, sec, sed, see, and tsst-1, the major SAg coding genes, and the obtained findings were statistically analyzed.
Results.
Phenotypic screening for SE production of 26 selected Staphylococci (15 isolated from the IE patients (10 S.
aureus and 5 coagulase negative staphylococci (CoNS)) and 11 from bacteremic patients (10 S.
aureus and 1 CoNS)) using ELISA revealed that 12/26 (46%) isolates were SE producers.
PCR analysis showed that 19 (73%) isolates were PCR positive for SAg genes with the highest prevalence of the sea gene (79%), followed by seb (63%) and tsst-1 (21%).
The least frequent gene was sed (5.3%).
Statistical correlations between bacteremic and IE isolates with respect to prevalence of SAgs showed no significant difference (P value = 0.139, effect size=0.572) indicating no specific association between any of the detected SAgs and IE.
Conclusion.
There is high prevalence of SEs among clinical isolates of Staphylococci recovered from patients suffering bacteremia and those with IE.
No significant difference was found among Staphylococcal isolates recovered from patients with bacteremia or IE regarding both phenotypic and genotypic detection of the tested SAgs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Elsherif, Heba M.& Helal, Zeinab H.& El-Ansary, Mona R.& Fahmy, Zeinab A.& Eltayeb, Wafaa N.& Radwan, Sahar…[et al.]. 2020. Staphylococcal Enterotoxins and Toxic Shock Syndrome Toxin-1 and Their Association among Bacteremic and Infective Endocarditis Patients in Egypt. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136399
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Elsherif, Heba M.…[et al.]. Staphylococcal Enterotoxins and Toxic Shock Syndrome Toxin-1 and Their Association among Bacteremic and Infective Endocarditis Patients in Egypt. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1136399
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Elsherif, Heba M.& Helal, Zeinab H.& El-Ansary, Mona R.& Fahmy, Zeinab A.& Eltayeb, Wafaa N.& Radwan, Sahar…[et al.]. Staphylococcal Enterotoxins and Toxic Shock Syndrome Toxin-1 and Their Association among Bacteremic and Infective Endocarditis Patients in Egypt. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136399
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136399
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر