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Essential Thrombocythemia Complicated by Occlusive Thrombosis of the Abdominal Aorta
المؤلفون المشاركون
Fenderson, Joshua L.
Geringer, Jamie
Osswald, Michael
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-26
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Introduction.
Essential thrombocythemia (ET) is a myeloproliferative neoplasm of excessive platelet production complicated by thrombohemorrhagic events.
Thrombosis typically occurs in small to medium vessels; thrombosis of large vessels is rare.
Case Presentation.
A 75-year-old woman with ET complicated by bilateral retinal vein occlusion was evaluated for fatigue, early satiety, and unintentional weight loss.
Her hypertension was well controlled, and her chronic lower extremity claudication from peripheral artery disease was stable.
She reported adherence to aspirin 81 mg and hydroxyurea 1000 mg daily, and her platelets (375 × 109/L) were at goal.
Bone marrow biopsy was consistent with ET without progression to myelofibrosis or leukemia.
CT abdomen demonstrated complete occlusion of the infrarenal aorta, extending into the common iliac arteries, with reconstitution of flow distally via collaterals.
The addition of clopidogrel, for platelet inhibition, and cilostazol, for claudication, caused symptom improvement without further thrombosis or bleeding.
Discussion.
There are few published reports of ET complicated by aortic thrombosis.
To our knowledge, this is the first report of aortic thrombosis occurring in an ET patient with normal platelet count on antiplatelet and cytoreductive therapies.
There is limited evidence to guide treatment, but medical management with triple antiplatelet therapy may be effective in selected patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Geringer, Jamie& Fenderson, Joshua L.& Osswald, Michael. 2019. Essential Thrombocythemia Complicated by Occlusive Thrombosis of the Abdominal Aorta. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136754
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Geringer, Jamie…[et al.]. Essential Thrombocythemia Complicated by Occlusive Thrombosis of the Abdominal Aorta. Case Reports in Hematology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1136754
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Geringer, Jamie& Fenderson, Joshua L.& Osswald, Michael. Essential Thrombocythemia Complicated by Occlusive Thrombosis of the Abdominal Aorta. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1136754
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136754
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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