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Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study
المؤلفون المشاركون
Yang, Guo-Yuan
Wu, Zhiyuan
Cheng, Lin
Tong, Shanbao
Miao, Fei
Sun, Junfeng
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-24
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Objective.
Neuroimaging studies revealed the functional reorganization or the structural changes during stroke recovery.
However, previous studies did not combine the functional and structural information and the results might be affected by heterogeneous lesion.
This study aimed to investigate functional activation-informed structural changes during stroke recovery.
Methods.
MRI data of twelve stroke patients were collected at four consecutive time points during the first 3 months after stroke onset.
Functional activation during finger-tapping task was used to inform the analysis of structural changes of activated brain regions.
Correlation between structural changes in motor-related activated brain regions and motor function recovery was estimated.
Results.
The averaged gray matter volume (aGMV) of contralesional activated brain regions and laterality index of gray matter volume (LIGMV) increased during stroke recovery, and LIGMV was positively correlated with Fugl-Meyer Index (FMI) at initial stage after stroke.
The aGMV of bilateral activated brain regions was negatively correlated with FMI during the stroke recovery.
Conclusion.
This study demonstrated that combining the stroke-induced functional reorganization and structural change provided new insights into the underlying innate plasticity process during stroke recovery.
Significance.
This study proposed a new approach to integrate functional and structural information for investigating the innate plasticity after stroke.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Zhiyuan& Cheng, Lin& Yang, Guo-Yuan& Tong, Shanbao& Sun, Junfeng& Miao, Fei. 2017. Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1136989
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Zhiyuan…[et al.]. Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study. BioMed Research International No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1136989
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Zhiyuan& Cheng, Lin& Yang, Guo-Yuan& Tong, Shanbao& Sun, Junfeng& Miao, Fei. Functional Activation-Informed Structural Changes during Stroke Recovery: A Longitudinal MRI Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1136989
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136989
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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