Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years
المؤلفون المشاركون
Ben Achour, Nedia
Rebai, Ibtihel
Raddadi, Sarra
Benrhouma, Hanene
Klaa, Hedia
Rouissi, Aida
Kraoua, Ichraf
Ben Youssef Turki, Ilhem
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Pediatric multiple sclerosis (pMS) is a rare demyelinating disorder with an onset before the age of 18 years.
In this study, we aimed to investigate the characteristics of pMS in Tunisian children.
Patients and Methods.
We conducted a retrospective study over 11 years (2005–2016) including all patients diagnosed with pMS according to the International Pediatric Multiple Sclerosis Study Group (IPMSSG) criteria of 2012 and followed up in a tertiary care research center.
Epidemiological, clinical, neuroimaging, laboratory, and therapeutic data were collected and analyzed.
Results.
There were 21 patients.
The male-female ratio was 1 : 3.
Mean age at onset was 11 years (range: 3–17 years).
Three patients had type 1 diabetes.
Polyfocal presentation was preponderant (81%) with motor dysfunction in 57% of patients.
Paroxysmal dystonia was noticed in 24%.
All patients were diagnosed with relapsing-remitting form.
Interferon beta was prescribed in 80% with a reduction of annual relapse rate.
Conclusion.
The annual incidence of pMS in Tunisian children aged below 18 years could be estimated as 0.05 per 100,000.
Singular features in our cohort were the frequent association with type 1 diabetes and the increased occurrence of dystonia.
Greater awareness of pMS may be helpful to improve management strategies of children and their families.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ben Achour, Nedia& Rebai, Ibtihel& Raddadi, Sarra& Benrhouma, Hanene& Klaa, Hedia& Rouissi, Aida…[et al.]. 2017. Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137012
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ben Achour, Nedia…[et al.]. Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137012
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ben Achour, Nedia& Rebai, Ibtihel& Raddadi, Sarra& Benrhouma, Hanene& Klaa, Hedia& Rouissi, Aida…[et al.]. Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137012
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137012
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر