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Reduction of Skeletal Muscle Power in Adolescent Males Carrying H63D Mutation in the HFE Gene
المؤلفون المشاركون
Antosiewicz, J.
Flis, Damian Jozef
Adamkiewicz-Drozynska, Elzbieta
Luszczyk, Marcin
Kaczorowska-Hac, Barbara
Milosz, Ewa
Ziemann, Ewa
Laskowski, Radoslaw
Rokicka-Hebel, Magdalena
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Iron overload resulting from the mutation of genes involved in iron metabolism or excess dietary intake has been reported to negatively influence human physical performance.
The aim of this study was to test the hypothesis that adolescents bearing a hemochromatosis gene (HFE) mutation in contrast to adults with the same mutation will not experience iron accumulation and their aerobic capacity will be similar to that of age-matched controls.
Thirteen boys participated in the study.
Seven of them are carriers of H63D mutation in the HFE gene and six were wild type.
Fitness levels were assessed using the cardiopulmonary exercise test.
In addition, iron status and inflammatory markers were determined.
We observed that cardiovascular fitness was significantly lower in the group bearing the HFE mutation compared to the control group.
Moreover, the HFE mutation group achieved lower maximal power output compared to the control group.
There were no differences in blood ferritin concentrations between the two groups which indicates similar amounts of stored iron.
Obtained data do not confirm our hypothesis.
On the contrary, it was demonstrated that HFE mutation is associated with a lower level of aerobic capacity, even in the absence of iron accumulation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luszczyk, Marcin& Kaczorowska-Hac, Barbara& Milosz, Ewa& Adamkiewicz-Drozynska, Elzbieta& Ziemann, Ewa& Laskowski, Radoslaw…[et al.]. 2017. Reduction of Skeletal Muscle Power in Adolescent Males Carrying H63D Mutation in the HFE Gene. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1137553
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luszczyk, Marcin…[et al.]. Reduction of Skeletal Muscle Power in Adolescent Males Carrying H63D Mutation in the HFE Gene. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1137553
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luszczyk, Marcin& Kaczorowska-Hac, Barbara& Milosz, Ewa& Adamkiewicz-Drozynska, Elzbieta& Ziemann, Ewa& Laskowski, Radoslaw…[et al.]. Reduction of Skeletal Muscle Power in Adolescent Males Carrying H63D Mutation in the HFE Gene. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1137553
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137553
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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