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Novel Model to Predict the Prognosis of Patients with Stage II–III Colon Cancer
المؤلفون المشاركون
Zhong, Huage
Xu, Yansong
Liang, Fangfang
Tang, Weizhong
Chen, Yi
Wang, Zhen
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Different opinions exist on the relationship between the C-reactive protein-to-albumin ratio (CAR) and the prognosis of colon cancer.
This study is aimed at evaluating the relationship between CAR and prognosis of stage II–III colon cancer and establishing a clinical prognosis model.
Patients were randomised to a training set (566 cases) and validation set (110 cases).
The relationship between CAR and clinicopathological variables was calculated, and the Kaplan-Meier method was used to analyse the overall survival (OS) rate of colon cancer.
In the training set, colon cancer independent risk factors were included in the prognosis model and then tested in the validation set.
The accuracy and discrimination of the model were assessed using the C-index and calibration curves.
Compared with patients with low CAR, patients with high CAR showed significantly poorer survival (P=0.020).
In the multivariate analysis, CAR, carcinoembryonic antigen (CEA), lymph node metastasis, operation mode, and perineural invasion were identified as independent prognostic indicators and adopted to establish the prediction model.
The C-index of the nomogram for predicting OS reached 0.751 in the training set and 0.719 in the validation set.
The calibration curve exhibited good consistency.
In the present study, the CAR may be an independent prognostic factor for stage II–III colon cancer, and the nomogram has a certain predictive value.
However, further prospective large-sample research needs to be conducted to validate our findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Yansong& Liang, Fangfang& Chen, Yi& Wang, Zhen& Zhong, Huage& Tang, Weizhong. 2020. Novel Model to Predict the Prognosis of Patients with Stage II–III Colon Cancer. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1137673
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Yansong…[et al.]. Novel Model to Predict the Prognosis of Patients with Stage II–III Colon Cancer. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1137673
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Yansong& Liang, Fangfang& Chen, Yi& Wang, Zhen& Zhong, Huage& Tang, Weizhong. Novel Model to Predict the Prognosis of Patients with Stage II–III Colon Cancer. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1137673
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137673
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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